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Research
Innate immune activation occurs in acute food protein–induced enterocolitis syndrome reactionsFood reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system
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Spatial clustering of notified tuberculosis in Ethiopia: A nationwide studySubstantial spatial clustering of notified tuberculosis was detected at region, zone and district level in Ethiopia
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Longitudinal Cognitive Performance in Individuals at Ultrahigh Risk for Psychosis: A 10-year Follow-upThe onset of psychosis was not associated with deterioration in cognitive ability
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The public health control of scabies: priorities for research and actionScabies causes considerable morbidity and leads to severe bacterial infection and immune-mediated disease
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Human genetics of leishmania infectionsGWAS results provide firm confirmation for the importance of antigen presentation and the regulation of IFNγ in determining the outcome of Leishmania infections
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Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy ResponsesImmunotherapies have revolutionized cancer treatment. In particular, immune checkpoint therapy (ICT) leads to durable responses in some patients with some cancers. However, the majority of treated patients do not respond. Understanding immune mechanisms that underlie responsiveness to ICT will help identify predictive biomarkers of response and develop treatments to convert non-responding patients to responding ones. ICT primarily acts at the level of adaptive immunity. The specificity of adaptive immune cells, such as T and B cells, is determined by antigen-specific receptors.
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Clinical description and outcomes of Australian children with invasive group a streptococcal diseaseInvasive group A streptococcal infection in Australian children is frequently severe and has a high long-term morbidity burden
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Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflowsSystematic comparison of recovered cell types and their transcriptional profiles across the workflows has highlighted protocol-specific biase
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Aural toilet (ear cleaning) for chronic suppurative otitis mediaChronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and often polymicrobial infection (involving more than one micro-organism) of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane.
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Immune function during early adolescence positively predicts adult facial sexual dimorphism in both men and womenOur results support a fundamental assumption that facial sexual dimorphism is an indicator of immune function during the development of facial sexual dimorphism