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Research

Serotonin and aggressive behaviour in children and adolescents: a systematic review

Findings were mixed, with support both for negative and for positive associations of central nervous 5-HT function with aggression in children and adolescents

Research

Safety and Immunogenicity of MF59-Adjuvanted Cell Culture-Derived A/H5N1 Subunit Influenza Virus Vaccine: Dose-Finding Clinical Trials in Adults and the Elderly

In adult and elderly participants, the full-dose aH5N1c vaccine formulation was well tolerated and met US and European licensure criteria for pandemic vaccines

Research

Mothers’ understanding of infant feeding guidelines and their associated practices: A qualitative analysis

The findings indicated that in spite of continued promotion of the AIFG over the past ten years achieving the around six months guideline is challenging

Research

Serotonergic contributions to human brain aggression networks

We investigated the influence of brain serotonin modulation and MAOA genotype on functional amygdala connectivity during aggressive behavior

Research

Multiomics and Systems Biology Are Needed to Unravel the Complex Origins of Chronic Disease

In this concept paper, we discuss multiomic approaches to studying immune dysregulation and highlight some of the challenges and opportunities

Research

Challenges to curing primary brain tumours

The seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment in brain tumours

Research

Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: Clinical Review

Clinical presentations and genetic variations in Cyclin-dependent kinase-like 5 deficiency disorder based on a systematic literature review and experience

Research

Identification of the determinants of incomplete vaccination in Australian children

Most parents are supportive of vaccination. Sociodemographic factors may contribute more to the risk of incomplete vaccination than attitudes or beliefs.

Research

Production of IgG2 Antibodies to Pneumococcal Polysaccharides After Vaccination of Treated HIV Patients May Be Augmented by IL-7Rα Signaling in ICOS + Circulating T-Cells

Our findings suggest that utilization of IL-7 by cTFH cells affects production of IgG2 antibodies to PPV23 antigens in some HIV patients

Research

The epidemiological transition in Papua New Guinea: new evidence from verbal autopsy studies

Our results indicate immediate priorities for health service planning and for strengthening of vital registration systems