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Research

A novel technique of serial biopsy in mouse brain tumour models

Here we describe a method by which serial biopsy can be used to validate response to dacomitinib treatment in vivo using a mouse glioblastoma model

Research

Population-based estimates of the effectiveness of pneumococcal vaccination in Australia

Australia’s Childhood Immunisation Register (ACIR) is one of only a handful of national immunisation registers world-wide.

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International consensus (ICON) on: Clinical consequences of mite hypersensitivity, a global problem

The objectives of this document are to highlight aspects of mite biology that are clinically relevant and to update the current knowledge on mite allergens

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What is the evidence for managing tone in young children with, or at risk of developing, cerebral palsy: a systematic review

To conduct a systematic review of the evidence for the management of tone in infants 0-24 months of age, with or at risk of developing cerebral palsy.

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Sialic acid-to-urea ratio as a measure of airway surface hydration

We explored a robust method to estimate mucus hydration using sialic acid as a marker for mucin content.

Research

ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

Experimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes.

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Association between male genital anomalies and adult male reproductive disorders: a population-based data linkage study spanning more than 40 years

Undescended testes is associated with an increased risk of testicular cancer and male infertility, and decreased paternity

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Incidence and prevalence of falls in adults with intellectual disability living in the community: a systematic review

Synthesized findings demonstrate that people with intellectual disability, who live in community or residential settings, may fall more frequently, and at a younger age

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Use of bevacizumab as a single agent or in adjunct with traditional chemotherapy regimens in children with unresectable or progressive low-grade glioma

Bevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity