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Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia

Our study provides evidence that OT-82 is a promising new therapeutic strategy for a broad spectrum of high-risk pediatric acute lymphoblastic leukem…

A comparison of major trauma patient transport destination in metropolitan Perth, Western Australia

This study examines the characteristics and outcomes of major trauma patients between transport destinations

Human genetics of leishmania infections

GWAS results provide firm confirmation for the importance of antigen presentation and the regulation of IFNγ in determining the outcome of Leishmania…

Azithromycin Partially Mitigates Dysregulated Repair of Lung Allograft Small Airway Epithelium

Chronic airway injury and dysregulated repair programs are evident in airway epithelium obtained from patients with bronchiolitis obliterans syndrome

Putting ‘Justice’ in Recovery Capital: Yarning about Hopes and Futures with Young People in Detention

We must celebrate success and hope through a process of mapping and building recovery capital in the justice context at an individual and institution…

Global consensus on nutritional rickets: Implications for Australia

We conclude that updated global recommendations for therapy of nutritional rickets complement previously published position statements for Australia…

New genetic predictors for abacavir tolerance in HLA-B*57:01 positive individuals

We investigated immune and non-immune related genes to determine other factors required for the development of Abacavir hypersensitivity syndrome

Assessing the unified airway hypothesis in children via transcriptional profiling of the airway epithelium

Upper and lower airways are conserved in their transcriptional composition, and variations associated with disease are present in both nasal and trac…

The Demographic and Neurocognitive Profile of Clients Diagnosed With Fetal Alcohol Spectrum Disorder in PATCHES Paediatrics Clinics

The aim of this study was to describe the demographic and neurocognitive profile of the first 199 individuals diagnosed with FASD in PATCHES Paediatr…

Profile of severely growth-restricted births undelivered at 40 weeks in Western Australia

Higher levels of poor perinatal outcomes among FGR births highlight the importance of appropriate management including fetal growth monitoring