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Life in a time of COVID: retrospective examination of the association between physical activity and mental well-being in western Australians during and after lockdown

The aim of this study was to examine physical activity and sedentary behaviours during Western Australia's COVID-19 lockdown and their association wi…

Gene filtering strategies for machine learning guided biomarker discovery using neonatal sepsis RNA-seq data

Machine learning (ML) algorithms are powerful tools that are increasingly being used for sepsis biomarker discovery in RNA-Seq data. RNA-Seq datasets…

Gene dysregulation in acute HIV-1 infection – early transcriptomic analysis reveals the crucial biological functions affected

Transcriptomic analyses from early human immunodeficiency virus (HIV) infection have the potential to reveal how HIV causes widespread and lasting da…

Techniques and Processes Involved in Nanoencapsulation of Omega-3, -6, and -9 Fatty Acids

Omega fatty acids are essential for young children’s growth and development. They also have essential functions in cell receptors of membranes and re…

Sub-project Summary

An outline of ORIGINS' active and completed sub-projects.

Penicillin Team

The Penicillin Team are working to accelerate research and clinical trials to improve penicillin formulation and treatment methods, to end RHD.

Protocol for a nested case-control study design for omics investigations in the Environmental Determinants of Islet Autoimmunity cohort

The Environmental Determinants of Islet Autoimmunity (ENDIA) pregnancy-birth cohort investigates the developmental origins of type 1 diabetes (T1D),…

The effect of CFTR modulators on structural lung disease in cystic fibrosis

Newly developed quantitative chest computed tomography (CT) outcomes designed specifically to assess structural abnormalities related to cystic fibro…