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Research

Group A streptococcal vaccines: Paving a path for accelerated development

Vaccine prevention of GAS infections and their immunological complications has been a goal of researchers for decades.

Research

A "Candidate-Interactome" Aggregate Analysis of Genome-Wide Association Data in Multiple Sclerosis

The interaction between genotype and Epstein Barr virus emerges as relevant for multiple sclerosis etiology.

Research

Associations between Handedness and Cerebral Lateralisation for Language: A Comparison of Three Measures in Children

It has been suggested that quantitative measures of differential hand skill or reaching preference may provide more valid measures than traditional...

Research

The International Collaboration for Autism Registry Epidemiology (iCARE): Multinational Registry-Based Investigations of Autism Risk Factors and Trends

iCARE provides a unique, unprecedented resource in autism research that will significantly enhance the ability to detect environmental and genetic...

Research

Early Onset Binge Eating and Purging Eating Disorders: Course and Outcome in a Population-Based Study of Adolescents

Purging at age 17 and externalising behaviour problems at age 14 were the strongest predictors of eating disorder persistence to age 20.

Research

New findings in the pathogenesis of otitis media

This study was the first to concurrently identify middle ear pathogens in both bacterial biofilm and intracellularly in the middle ear mucosa of children and to identify extensive DNA stranding in the MEF from children with AOM

Research

Early loss of the glucagon response to hypoglycemia in adolescents with type 1 diabetes

The objective was to assess the glucagon response to hypoglycemia and identify influencing factors in patients with type 1 diabetes compared with nondiabetic...

Research

Descriptive epidemiology of cleft lip and cleft palate in Western Australia

These data provide a picture of the prevalence of OFCs in WA since 1980, and provide a useful reference for OFC data in Australia and internationally.

Research

Genetic polymorphisms and childhood acute lymphoblastic leukemia: GWAS of the ESCALE study (SFCE)

Acute lymphoblastic leukemia (ALL) accounts for approximately 80% of the acute leukemia (AL) overall cases per year in France. We report the results of a...

Research

Cholesteryl ester transfer protein gene polymorphisms increase the risk of fatty liver in females independent of adiposity

Environmental factors including excessive caloric intake lead to disordered lipid metabolism and fatty liver disease.