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MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63We hypothesized that reactivation of p53 by inhibition of its negative regulator will result in p53-mediated growth arrest and apoptosis.
Research
Peptides targeting the mitogen-activated protein kinase pathway (JNK/JUN) fail to reduce infarct volume after permanent MCAO in sprague dawley ratsIn this study we have assessed the ability of two TAT-fused peptides to reduce infarct volume and improve functional outcome following permanent ischaemia.
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Symptomatic viral infection is associated with impaired response to treatment in children with acute asthmaThe objective of this study was to examine the influence of viral respiratory infection (VRI) on treatment response in acute asthma in children.
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Changes in the clinical and epidemiological features of group A streptococcal bacteraemia in Australia's northern territoryWe aimed to measure the incidence and severity of invasive Group A Strep disease in the NT since 1996.
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Antecedent hypoglycaemia does not diminish the glycaemia-increasing effect and glucoregulatory responses of a 10 s sprint in people with type 1 diabetesThe purpose of this study was to investigate whether antecedent hypoglycaemia impairs the glycaemia-raising effect of a 10 s sprint in individuals with type...
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Teacher–Child Relationship, Parenting, and Growth in Likelihood and Severity of Physical Aggression in the Early School YearsThis study investigated the likelihood of children showing problems with parent-rated physical aggression, and on the severity of problems, for 374 children.
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Does walkable neighbourhood design influence the association between objective crime and walking?This study examined associations between objective crime and walking, controlling for the characteristics of walkable neighbourhoods.
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Serum phosphorylated neurofilament-heavy chain levels in multiple sclerosis patientsWe evaluated whether the measurement of serum phosphorylated neurofilament heavy chain (pNF-H) titre is likely to be a valid biomarker of axonal injury in...
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Using Systems Theory to Understand and Respond to Family Influences on Children's Bullying BehaviorThis article addresses Systems Theory as it applies to school-age children's bullying behavior.
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'I can sit and talk to her': Aboriginal people, chronic low back pain and healthcare practitioner communicationChronic low back pain (CLBP) is a complex issue to manage in primary care and under-researched in Aboriginal populations.