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This study aimed to determine how pulmonary inflammation & infection impacts on ventilation distribution throughout early life in people with cystic fibrosis.

Recent technological advances in equipment design have produced gains in popularity for this test among cystic fibrosis (CF) researchers and clinicians...

This letter addresses the recommendations by the American Thoracic Society & European Respiratory Society in 2005, that patients must wait 15-60mins between...

The pathophysiology of BPD has changed in recent years as advances in neonatal care have led to increased survival of smaller, more preterm, infants who...

Ventilated preterm infant lungs are vulnerable to overdistension and underinflation.

Non-invasive techniques for measuring lung mechanics in infants are needed for a better understanding of lung growth and function...

This editorial article addresses chronic obstructive pulmonary disease and lung function testing in Aboriginal Australians.

Differences in the assessment of pediatric pain between children, parents, nurses, and independent observers in the acute postoperative setting

To better characterise prematurity-associated lung disease, adult spirometry phenotype classifications (obstructive lung disease, preserved ratio impaired spirometry and dysanapsis) have been applied to children born preterm. It is unknown how these phenotypes track over time.

Functional studies of how early-life interventions shape the airway microbiome remain scarce. Here, we performed metagenomic sequencing of 704 longitudinal nasal swabs from infants with and without cystic fibrosis (CF) to construct and characterize a non-redundant gene atlas of the infant nasal microbiome. We aimed to determine how the nasal microbiome is perturbed by early therapies, as CF is commonly treated with inhaled hypertonic saline to improve mucociliary clearance.