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Research

Exhaled breath temperature in healthy children is influenced by room temperature and lung volume

Exhaled breath temperature (EBT) has been proposed for the non-invasive assessment of airway inflammation

Research

Changes in lung volume during spells in children with Tetralogy of Fallot under general anesthesia

To describe the changes in end-expiratory lung volume and ventilation inhomogeneities during spells in three children with Tetralogy of Fallot.

Research

Lung function testing in preschool-aged children with cystic fibrosis in the clinical setting

This study investigated the nature and prevalence of atypical pain responses in Rett syndrome and their relationships with specific MECP2 mutations.

News & Events

My child is wheezing – what should I do?

Almost 50 per cent of preschool children will experience at least one episode of wheeze, a whistling sound produced by the airways during breathing.

Research

The Impact of Modulator therapy from Early life on lung health trajectories in Cystic Fibrosis (TIME-CF)

Cystic fibrosis is an inherited condition that results in chronic lung disease. In recent years, a new type of medication called CFTR modulators has become available.

Research

Western Australia Paediatric Bronchiectasis Cohort

Bronchiectasis is a chronic lung disease that impairs quality of life and reduces life expectancy.

Research

FINGERPRINT: FINdinG Early markers of Respiratory disease for survivors of PReterm birth which IdeNtify Treatable traits

This research project will investigate the traits of preterm lung disease, looking into the long-term lung health of children born preterm, aiming to identify traits that could help guide better treatments in the future.

Researchers sound the alarm as vaping fad explodes

Research into the potential health impacts of vaping is starting to back up concerns that electronic cigarettes (e-cigarettes) are not as benign as many people think.

Research

A brief history of MECP2 duplication syndrome: 20-years of clinical understanding

MECP2 duplication syndrome (MDS) is a rare, X-linked, neurodevelopmental disorder caused by a duplication of the methyl-CpG-binding protein 2 (MECP2) gene-a gene in which loss-of-function mutations lead to Rett syndrome (RTT). MDS has an estimated live birth prevalence in males of 1/150,000.

Research

Normal values of respiratory oscillometry in South African children and adolescents

Noninvasive measurement of respiratory impedance by oscillometry can be used in young children aged from 3 years and those unable to perform forced respiratory manoeuvres. It can discriminate between healthy children and those with respiratory disease. However, its clinical application is limited by the lack of reference data for African paediatric populations. The aim of the present study was to develop reference equations for oscillometry outcomes in South African children and adolescents.