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Parent-Child Interactions May Help to Explain Relations Between Parent Characteristics and Clinically Observed Child Autistic BehavioursThe importance of supporting parent-child interactions has been noted in the context of prodromal autism, but little consideration has been given to the possible contributing role of parental characteristics, such as psychological distress. This cross-sectional study tested models in which parent-child interaction variables mediated relations between parent characteristics and child autistic behaviour in a sample of families whose infant demonstrated early signs of autism.
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Vitamin D is crucial for maternal care and offspring social behaviour in ratsThese data highlight that early life levels of vitamin D are an important consideration for maternal behavioural adaptations as well as offspring neuropsychiatry
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Cytokine levels and associations with symptom severity in male and female children with autism spectrum disorderASD's are complex, pervasive and heterogeneous neurodevelopmental conditions with varying conditions, trajectories, significant male bias and unknown etiology.
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Pre-emptive intervention versus treatment as usual for infants showing early behavioural risk signs of autism spectrum disorderA pre-emptive intervention for the autism spectrum disorder prodrome had no immediate treatment effect on early autism spectrum disorder symptoms
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The effect of functioning on Quality of Life Inventory-Disability measured quality of life is not mediated or moderated by parental psychological distressThe measurement of quality of life (QOL) in children with intellectual disability often relies upon proxy report via caregivers. The current study investigated whether caregiver psychological distress mediates or moderates the effects of impairment on their ratings of QOL in children with intellectual disability.
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Genetic counseling as preventive intervention: toward individual specification of transgenerational autism riskAlthough autism spectrum disorders (ASD) are among the most heritable of all neuropsychiatric syndromes, most affected children are born to unaffected parents. Recently, we reported an average increase of 3-5% over general population risk of ASD among offspring of adults who have first-degree relatives with ASD in a large epidemiologic family sample.
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Common variation contributes to the genetic architecture of social communication traitsSocial communication difficulties represent an autistic trait that is highly heritable and persistent during the course of development.
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A "bottom-up" approach to aetiological research in autism spectrum disordersAutism spectrum disorders (ASD) are currently diagnosed in the presence of impairments in social interaction and communication, and a restricted range of...
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Associations between Handedness and Cerebral Lateralisation for Language: A Comparison of Three Measures in ChildrenIt has been suggested that quantitative measures of differential hand skill or reaching preference may provide more valid measures than traditional...
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Do hypertensive diseases of pregnancy disrupt neurocognitive development in offspring?The current study sought to determine whether gestational hypertension and pre-eclampsia are associated with neurocognitive outcomes in middle childhood.