Reports and Findings (Published Research)

Washing machines could support skin health for First Nations people – if we get the wash settings right

Rosemary Kate Rachel Wyber Summer Burgess MBChB MPH FRACGP PhD PhD PhD Senior Research Fellow Postdoctoral Research Officer Senior Research Fellow 0422 630 458 Kate.Summer@thekids.org.au Rachel.Burgess@thekids.org.au Senior Research Fellow

Developing better tools for monitoring housing-related health issues in remote communities

Kate Rosemary Summer Wyber PhD MBChB MPH FRACGP PhD Postdoctoral Research Officer Senior Research Fellow 0422 630 458 Kate.Summer@thekids.org.au Postdoctoral Research Officer Senior Research Fellow Kate is a post-doc researcher with the Strep A

HOMEFREE: Scaling-Up Evidence-Based Guidelines for IV-to-Oral Antibiotic Switch in Hospitalised Children, an Implementation Study Protocol

Around half of children admitted to hospital receive intravenous antibiotics, contributing to higher costs, vascular access complications and longer hospital stays.

Paediatric anaesthesia and the developing brain

Concerns persist regarding the potential long-term effects of general anaesthesia on brain development in children. This narrative review summarises recent preclinical and clinical evidence (2019-25) and updates consensus messages.

Long-term outcomes of childhood encephalitis in Australia: burden and predictors from the Australian childhood encephalitis (ACE) prospective multicentre cohort

Encephalitis is inflammation of the brain parenchyma with heterogenous aetiology and presentation. In children, it often leads to short-term residual neurological deficits, however clinical predictors of adverse long-term outcome are not fully understood.

Restricting outdoor advertising of unhealthy food: feasibility of using a nutrition classification system in Australia

Exposure to food advertising is associated with consumption. Globally, most outdoor food advertisements feature unhealthy foods or beverages. As Australian local government areas begin developing restriction policies, the feasibility of applying nutrient-based Nutrition Classification Systems to outdoor advertising requires evaluation.

Optimising Asparaginase Use and Managing Hypersensitivity in Australasia—A Clinical Practice Guideline From the Australian and New Zealand Children's Haematology/Oncology Group

Asparaginase is a critical component of modern multi-agent chemotherapy regimens for paediatric acute lymphoblastic leukaemia and lymphoblastic lymphoma, with inadequate exposure leading to inferior patient outcomes.

Single-cell RNA sequencing profiles drug activity within spatially engineered 3D cultures

Spatial transcriptomic techniques provide a wealth of information useful in guiding drug development, while three-dimensional (3D) cell cultures have demonstrated power in accelerating drug approvals. However, techniques for robust spatial analysis of 3D cultures are limited. Here, we present a transfection-based method for constructing cellular spheroids through a layer-by-layer approach, in which DNA barcodes encode the spatial positioning of cells.

Trends in prevalence and predictors of anemia among school-aged children in Tanzania: analysis of 2019–2023 cross-sectional surveys using a multilevel logistic regression model

Anemia constitutes a major global public health challenge among school-aged children with documented impacts on psychomotor development, academic achievement, susceptibility to infections, and long-term economic productivity. This study presents nationally representative findings on the prevalence and determinants of anemia among school children aged 5-16 years in mainland Tanzania.

The National Allergy Centre of Excellence–Addressing Australia's Allergy Burden

Australia has one of the highest rates of food allergy, anaphylaxis hospital admissions and anaphylaxis fatalities worldwide. These trends and sustained advocacy prompted a 2019 Parliamentary Inquiry into Allergies and Anaphylaxis. Among 250 submissions, the Centre for Food Allergy Research called for a national research-coordinating centre and comprehensive allergy research funding.