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We have recently published a paper identifying precursor populations in peripheral lung (2017), and have also discovered that these populations can be found in multiple tissues.
The relative importance of respiratory viral infections vs inhalant allergy in asthma pathogenesis is the subject of ongoing debate.
Hematopoiesis occurs in a complex bone marrow microenvironment in which bone marrow stromal cells provide critical support to the process through direct cell...
To investigate the immune capabilities of peripheral tissue DCs generated in vivo from the BM of UV-irradiated mice, chimeric mice were established.
The respiratory tract is an attractive target organ for novel diagnostic and therapeutic applications with nano-sized carriers, but their immune effects and...
Inflammatory mediators from peripheral tissues may control dendritic cell (DC) development in the bone marrow.
Airway epithelial cells act through multiple mechanisms to function as an important component of the pulmonary defence strategy that is crucial...
This protocol adapted an experimental animal model of disease for sensitization to ovalbumin during the immediate post-weaning period beginning at 21 days of age
Atopic asthma, which is at its highest prevalence during childhood/young adulthood, represents the main focus of this review.
Respiratory IgE-sensitization to innocuous antigens increases the risk for developing diseases such as allergic asthma.