Asthma affects millions worldwide. Long non-coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma and respiratory il…
Spatial transcriptomic techniques provide a wealth of information useful in guiding drug development, while three-dimensional (3D) cell cultures have…
Previous research has shown that immune development during the first week of life, i.e. ontogeny, is progressive, consistent and robust, involving la…
Over the last two decades, transcriptomics has become a standard technique in biomedical research. We now have large databases of RNA-seq data, accom…
Seven female individuals with multiple congenital anomalies, developmental delay and/or intellectual disability have been found to have a genetic var…
Mutations in the TANGO2 gene cause an autosomal recessive disorder characterised by developmental delay, stress-induced episodic rhabdomyolysis, and…
Expression of the compact mitochondrial genome is regulated by nuclear encoded, mitochondrially localized RNA-binding proteins (RBPs). RBPs regulate…
The specific role of chromatin modifying factors in the timely execution of transcriptional changes in gene expression to regulate organ size remains…