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Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells Abstract Background Mutations in
Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children
The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials
The potential of antisense oligonucleotide therapies for inherited childhood lung diseases Antisense oligonucleotides (AOs) are an emerging
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Parent of a year 7 student? Why now is the best time to talk to your child about drinkingYear 7 is a time of big change and challenges - and it's also the best time to start talking about alcohol.
Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis Abstract Calprotectin, the major
BAL Inflammatory Markers Can Predict Pulmonary Exacerbations in Children With Cystic Fibrosis Background: Pulmonary exacerbations in cystic
Structural determinants of long term functional outcomes in young children with cystic fibrosis BACKGROUND: Accelerated lung function decline in
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Perth researchers lead world-first clinical trial in Chile to stop COVID-19 outbreaksPerth researchers are leading an international clinical trial focused on preventing the spread of COVID-19 by testing the effectiveness of the drug interferon in reducing the infectiousness of people who contract the virus.
Quantitative assessment of airway dimensions in youngchildren with cystic fibrosis lung disease using chestcomputed tomography Abstract Objective: To
Lung Clearance Index and Structural Lung Disease on Computed Tomography in Early Cystic Fibrosis Abstract Rationale: The lung clearance index is a
Helping families to unlock the mental and physical health benefits of connecting with nature and community through outdoor play - easily, and locally.
Dissecting the regulation of bile-induced biofilm formation in Staphylococcus aureus. Aspiration of bile into the cystic fibrosis (CF) lung has
Research
The Missing Piece Surveillance Study: A surveillance study for strep A pharyngitis and impetigo in the Kimberley, AustraliaThe Missing Piece Surveillance Study is a prospective surveillance study to determine the concurrent burden of skin and throat infections in children, from two remote communities in Northern Australia.
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PCV10 elicits Protein D IgG responses in Papua New Guinean children but has no impact on NTHi carriage in the first two years of lifeNasopharyngeal colonisation with nontypeable Haemophilus influenzae (NTHi) is associated with development of infections including pneumonia and otitis media. The 10-valent pneumococcal conjugate vaccine (PCV10) uses NTHi Protein D (PD) as a carrier. Papua New Guinean children have exceptionally early and dense NTHi carriage, and high rates of NTHi-associated disease.
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Topical antibiotics for chronic suppurative otitis mediaWe are uncertain about the effectiveness of topical antibiotics in improving resolution of ear discharge in patients with chronic suppurative otitis media
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Sulfamethoxazole-Trimethoprim (Cotrimoxazole) for Skin and Soft Tissue Infections Including Impetigo, Cellulitis, and AbscessWe conducted a systematic review of clinical trials and observational studies that address the utility of SXT for SSTI treatment, caused by either GAS or MRSA
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Epidemiology and mortality of staphylococcus aureus Bacteremia in Australian and New Zealand childrenDescribe the epidemiology of Staphylococcus aureus bacteremia in children and adolescents younger than 18 years from Australia and New Zealand