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Research

Taste-Masked Flucloxacillin Powder Part 2: Formulation Optimisation Using the Mixture Design Approach and Storage Stability

Flucloxacillin is prescribed to treat skin infections but its highly bitter taste is poorly tolerated in children. This work describes the application of the D-optimal mixture experimental design to identify the optimal component ratio of flucloxacillin, Eudragit EPO and palmitic acid to prepare flucloxacillin taste-masked microparticles that would be stable to storage and would inhibit flucloxacillin release in the oral cavity while facilitating the total release of the flucloxacillin load in the lower gastrointestinal tract.

Research

Liquor landscapes: Does access to alcohol outlets influence alcohol consumption in young adults?

Longitudinal analyses showed that for each increase in liquor stores over time, alcohol consumption increased

Research

Brief Report: Burden of Care in Mothers of Children with Autism Spectrum Disorder or Intellectual Disability

Mothers of children with autism spectrum disorder or intellectual disability have higher rates of treatment episodes for psychiatric disorders

Research

Sun exposure and its effects on human health: Mechanisms through which sun exposure could reduce the risk of developing obesity and cardiometabolic dysfunction

The cardiometabolic protective effects of ultraviolet radiation and mechanistic pathways through which ultraviolet radiation could be beneficial.

Research

Hospital admissions and gestational age at birth: 18 Years of follow up in Western Australia

This effect of gestational age on rehospitalisation for infants born preterm is highest in the first year post-discharge, but almost disappeared by adolescence

Research

Antibody and cell-mediated immunity to pertussis 4 years after monovalent acellular pertussis vaccine at birth

In the longest reported follow-up of infants who received aP vaccine at birth, we found a trend to lower PT IgG antibodies post booster compared with receipt...

ORIGINS Biobank

The ORIGINS Biobank is collecting biological samples from participant families at 10 timepoints between the time of pregnancy and the child turning five years of age.

News & Events

Mental health disorders on rise in parents

A unique Australian study has found that the prevalence of mental health disorders in parents of infants rose dramatically between 1990 and 2005.

Research

Preventing perioperative respiratory complications in children with recurrent respiratory symptoms

Elizabeth Graham Smith Hall PhD, MSc, BSc BAppSci PhD CRFS FANZSRS FThorSoc FERS Program Manager Honorary Research Associate 08 6319 1178

BANK CF

The AREST CF project focuses on the assessment, treatment and prevention of CF lung disease in children under the age of seven.