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Research

Systemic antibiotics for chronic suppurative otitis media

To assess the effects of systemic antibiotics for people with chronic suppurative otitis media.

Research

Topical antiseptics for chronic suppurative otitis media

To assess the effects of topical antiseptics for people with chronic suppurative otitis media

Research

How New and Expecting Fathers Engage With an App-Based Online Forum: Qualitative Analysis

These data show that fathers are prepared to use a breastfeeding-focused online forum in a variety of ways to facilitate social support

Research

Evaluation of a public education campaign to support parents to reduce adolescent alcohol use

The Parents, Young People and Alcohol campaign achieved high awareness and positively influenced parental outcomes

Research

Immunogenicity and safety of single-dose, 13-valent pneumococcal conjugate vaccine in pediatric and adolescent oncology patients

All children who are receiving therapy for cancer should receive a single dose of PCV13 as soon as possible after diagnosis, regardless of prior PCV exposure.

Research

Burkholderia pseudomallei evades Nramp1 (Slc11a1)- and NADPH oxidase-mediated killing in macrophages and exhibits Nramp1-dependent virulence gene expression

Here we show that transfected macrophages stably expressing wild-type Nramp1 (Nramp1+) control the net replication of B. thailandensis, but not B. pseudomallei.

Research

High-dose intramuscular Vitamin D provides long-lasting moderate increases in serum 25-hydroxVitamin D levels and shorter-Term changes in plasma calcium

Intramuscular injection of a large bolus of Vitamin D effectively increases serum 25-hydroxyVitamin D levels without evidence of metabolic abnormality.

Research

The bioenergetics of inflammation: insights into obesity and type 2 diabetes

Diabetes mellitus is one of the most common chronic metabolic disorders worldwide, and its incidence in Asian countries is alarmingly high.

Research

An exposome perspective: Early-life events and immune development in a changing world

Here we review the historical origins of exposome research and define a new concept, the metaexposome