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Research

Acquired resistance during adoptive cell therapy by transcriptional silencing of immunogenic antigens

These findings suggest that tumor cells employ multiple epigenetic and genetic mechanisms to evade immune control

Research

Vitamin D is crucial for maternal care and offspring social behaviour in rats

These data highlight that early life levels of vitamin D are an important consideration for maternal behavioural adaptations as well as offspring neuropsychiatry

Research

The mask or the needle? Which induction should we go for?

For children scheduled for elective surgery, intravenous induction has significant advantages with regards to reduced respiratory adverse events

Research

An investigation of the determinants of quality of life in adolescents and young adults with Down syndrome

Quality of life of young people with Down syndrome was most negatively associated with burden of medical conditions, but also with lack of friendships

Research

Effectiveness, Acceptability, and Feasibility of Digital Health Interventions for LGBTIQ+ Young People: Systematic Review

Young people (aged 12-25 years) with diverse sexuality, gender, or bodily characteristics, such as those who identify as lesbian, gay, bisexual, transgender, intersex, or queer (LGBTIQ+), are at substantially greater risk of a range of mental, physical, and sexual health difficulties compared with their peers. Digital health interventions have been identified as a potential way to reduce these health disparities.

Research

Development and Assessment of Cumulative Risk Measures of Family Environment and Parental Investments in the Longitudinal Study of Australian Children

This study aimed to derive and assess summary indices of three domains of the family environment, including a Family Stress Index, Home Education Index and Parenting Index

Research

Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells

Apically located tight junctions in airway epithelium perform a fundamental role in controlling macromolecule migration through paracellular spaces.

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What are the position and power of supermarkets in the Australian food system, and the implications for public health? A systematic scoping review

This review synthesized the literature that describes the position and power of supermarkets in the Australian system, and the implications for public health.

Research

Associations between cardiovascular disease and its risk factors with hearing loss—A cross-sectional analysis

We investigate the relationship between hearing loss and cardiovascular disease risk factors.

Research

Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells

This study assessed an alternative approach, using a small scale halide assay that can be adapted for a personalized high throughput setting to analyze CFTR function of pAEC.

Research

Vaccine-preventable child deaths in New South Wales from 2005 to 2014: How much is preventable?

To identify and describe potentially vaccine-preventable child deaths in New South Wales (NSW).

Research

CDKL5 variants: Improving our understanding of a rare neurologic disorder

Providing new insights into the interpretation of genetic variants in a rare neurologi disorder, in the contexts of population sequencing data.