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Research

Tackling the Burden of Osteoarthritis as a Health Care Opportunity in Indigenous Communities-A Call to Action

Osteoarthritis is a highly prevalent and disabling disease, causing a significant individual and socioeconomic burden worldwide. Until now, there has been a dearth of research exploring the impact of osteoarthritis in global Indigenous communities.

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Pre-emptive intervention versus treatment as usual for infants showing early behavioural risk signs of autism spectrum disorder

A pre-emptive intervention for the autism spectrum disorder prodrome had no immediate treatment effect on early autism spectrum disorder symptoms

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Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained

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Prebiotics: mechanisms and preventive effects in allergy

In this review, we describe both the mechanisms and the therapeutic evidence from preclinical and clinical studies exploring the role of prebiotics in allergy prevention

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Preterm birth: Born too soon for the developing airway epithelium

This review examines the consequences of preterm birth on the airway epithelium and explores the clinical relevance of currently available models

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Impact of Childhood Pneumococcal Conjugate Vaccine on Nonnotified Clinically Suspected Invasive Pneumococcal Disease in Australia

This study provides a quantitative estimate of the total burden of invasive pneumococcal disease preventable by vaccination programs in Australia

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The pervasive effects of timing of parental mental health disorders on adolescent deliberate self-harm risk

This study shows that timing is important for understanding intergenerational transmission of deliberate self-harm risk

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Exposure to Solar UVR Suppresses Cell-Mediated Immunization Responses in Humans: The Australian Ultraviolet Radiation and Immunity Study

Higher UVR exposure at antigen sensitization was associated with a reduced delayed-type hypersensitivity response and altered T helper type 17 kinetics

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MicroRNA Signatures in Malignant Pleural Mesothelioma Effusions

These results suggest that the expression of miR-143, miR-210, and miR-200c in PE cells might provide a signature for diagnosing malignant pleural mesothelioma