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Research

Use of remote monitoring with continuous glucose monitoring in young children with Type 1 diabetes: the parents’ perspective

Parents of primary school children reported that using remote monitoring and continuous glucose monitoring was a mostly beneficial experience

Research

QuantSeq. 3′ Sequencing combined with Salmon provides a fast, reliable approach for high throughput RNA expression analysis

QuantSeq, coupled with a fast quantification method such as Salmon, should provide a viable alternative to traditional RNA-Seq in many applications

Research

Allograft outcome following repeat transplantation of patients with non-adherence-related first kidney allograft failure: a population cohort study

The associations between causes of first allograft failure and acute rejection-related and non-adherence-related allograft failure following re-transplantation

Research

PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours

Our findings define PTPN2 as a target for bolstering T-cell-mediated anti-tumour immunity and CAR T-cell therapy against solid tumours.

Research

Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease

We report for the first time that a common stress condition, such as viral infection, can exacerbate mitochondrial dysfunction in a genetic model of mitochondrial disease

Research

Genome mining and characterisation of a novel transaminase with remote stereoselectivity

Here we report a novel ω-transaminase discovered in a marine sponge Pseudovibrio sp. isolate

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Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained

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Prebiotics: mechanisms and preventive effects in allergy

In this review, we describe both the mechanisms and the therapeutic evidence from preclinical and clinical studies exploring the role of prebiotics in allergy prevention

Research

Attitudes about and access to influenza vaccination experienced by parents of children hospitalised for influenza in Australia

Improving parents’ and providers’ knowledge and confidence in influenza vaccination safety, efficacy, and benefits should be prioritised

Research

Impact of Childhood Pneumococcal Conjugate Vaccine on Nonnotified Clinically Suspected Invasive Pneumococcal Disease in Australia

This study provides a quantitative estimate of the total burden of invasive pneumococcal disease preventable by vaccination programs in Australia