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Research

Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained

Research

Exposure to Solar UVR Suppresses Cell-Mediated Immunization Responses in Humans: The Australian Ultraviolet Radiation and Immunity Study

Higher UVR exposure at antigen sensitization was associated with a reduced delayed-type hypersensitivity response and altered T helper type 17 kinetics

Research

Overcrowded housing: One of a constellation of vulnerabilities for child sexual abuse

The findings suggest that overcrowded living conditions are associated with an increased risk of sexual abuse for some children

Research

Immunogenicity and Safety of a Quadrivalent Meningococcal ACWY-tetanus Toxoid Conjugate Vaccine 6 Years After MenC Priming as Toddlers

One dose of MenACWY-TT boosts protection against MenC in primed children, is safe and extends protection against MenA, MenW and MenY

Research

Gamifying Breastfeeding for Fathers: Process Evaluation of the Milk Man Mobile App

The Milk Man app was an acceptable source of breastfeeding information and support that fathers and fathers-to-be are prepared to use throughout the perinatal period

Research

Acquired resistance during adoptive cell therapy by transcriptional silencing of immunogenic antigens

These findings suggest that tumor cells employ multiple epigenetic and genetic mechanisms to evade immune control

Research

MicroRNA Signatures in Malignant Pleural Mesothelioma Effusions

These results suggest that the expression of miR-143, miR-210, and miR-200c in PE cells might provide a signature for diagnosing malignant pleural mesothelioma

Research

The mask or the needle? Which induction should we go for?

For children scheduled for elective surgery, intravenous induction has significant advantages with regards to reduced respiratory adverse events

Research

Parent-reported health-related quality of life of children with Down syndrome: A descriptive study

To describe health-related quality of life of Australian children and adolescents with Down syndrome and compare it with norm-referenced data.

Research

Informing Intervention Strategies to Reduce Energy Drink Consumption in Young People: Findings From Qualitative Research

Determining young people's knowledge of energy drink (EDs), factors influencing ED consumption and intervention strategies to lower ED consuption in youth.