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Research
Use of Hybrid Closed Loop therapy in hypoglycaemia awarenessThis study will tell us if the use of a hybrid closed loop system can improve awareness of hypoglycaemia.
Research
Longitudinal Type 1 and 2 Diabetes Plasma and Serum RepositoryThe Serum & Plasma bank was established to provide a store of samples from subjects with diabetes as well as their families.
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Australian Childhood Diabetes DNA RepositoryCollecting DNA samples from Australian families affected by diabetes.
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Diabetes Translational ResearchThe year 2013 saw the progress in our research from purely lab-based studies towards taking a step closer to translational research.
Research
TrialNet: Pathway to PreventionThis study is helping us to learn how type 1 diabetes develop and ways to delay and prevent it.
Research
Investigating mortality rates and the incidence and risk factors of diabetes complications and co-morbidities during early adult life in a population based childhood onset diabetes cohortUsing the WA Data Linkage System to provide information of the incidence and relative risk of T1D co-morbidities and mortality during early adulthood.
Research
Undiagnosed Diseases Program (UDP) and Bringing the benefits of precision medicine to children in Western AustraliaWe have started a project utilising whole genome sequencing of undiagnosed children living in WA to provide a definitive diagnosis. A major challenge here is that the role and functions of the inter-genic regions of our genome (the remaining 98%) are relatively poorly understood.
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An unbiased exploration of the human regulatory landscapeWe are made up of hundreds of different cell types carrying out a diverse range of functions essential for organism survival. All the information required to specify the morphology, function and response to stimuli of these cells is encoded in identical copies of the genome. The process of gene regu
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Borderline Personality Disorder and Peers: A Scoping Review of Friendship, Victimization and Aggression StudiesBorderline personality disorder (BPD) is characterized by instability in interpersonal relationships. To date no reviews have scoped the extant research on peer relationship functioning for young people diagnosed with BPD or showing borderline personality features. The current review provides this scoping of studies on all facets of peer relationships, including friendship quality, peer victimization and bullying and peer aggression, and relevant studies of social–cognitive processes with relevance to peer relationships. From 282 studies identified up to August 2019, 39 studies were included for review.
Research
Preparing for Life: Plasma Proteome Changes and Immune System Development During the First Week of Human LifeNeonates have heightened susceptibility to infections. The biological mechanisms are incompletely understood but thought to be related to age-specific adaptations in immunity due to resource constraints during immune system development and growth. We present here an extended analysis of our proteomics study of peripheral blood-plasma from a study of healthy full-term newborns delivered vaginally, collected at the day of birth and on day of life (DOL) 1, 3, or 7, to cover the first week of life. The plasma proteome was characterized by LC-MS using our established 96-well plate format plasma proteomics platform.