Search
Research
Host-dependent resistance of Group A Streptococcus to sulfamethoxazole mediated by a horizontally-acquired reduced folate transporterDescribed antimicrobial resistance mechanisms enable bacteria to avoid the direct effects of antibiotics and can be monitored by in vitro susceptibility testing and genetic methods. Here we describe a mechanism of sulfamethoxazole resistance that requires a host metabolite for activity.
Research
A brief history of MECP2 duplication syndrome: 20-years of clinical understandingMECP2 duplication syndrome (MDS) is a rare, X-linked, neurodevelopmental disorder caused by a duplication of the methyl-CpG-binding protein 2 (MECP2) gene-a gene in which loss-of-function mutations lead to Rett syndrome (RTT). MDS has an estimated live birth prevalence in males of 1/150,000.
Research
The effect of endotracheal tubes versus laryngeal mask airways on perioperative respiratory adverse events in infants: A randomised controlled trialEvaluating the difference of the effects of Laryngeal mask airways compared to endotracheal tubes in older children (>1 year) in incidents of PRAE in infants.
Research
Early lung surveillance of cystic fibrosis: what have we learnt?Newborn screening (NBS) for cystic fibrosis (CF) provides an opportunity to commence management and therapeutic interventions significantly earlier
Research
Respiratory function and symptoms in young preterm children in the contemporary eraPreterm children have worse lung function than healthy controls
Research
Home oxygen therapy for infants and young children with acute bronchiolitis and other lower respiratory tract infections: The HiTHOx programRecent studies have demonstrated that some children with acute bronchiolitis can be successfully managed using home oxygen therapy.
Research
Vitamin D deficiency at 16 to 20 weeks' gestation is associated with impaired lung function and asthma at 6 years of ageThis paper examines whether a Vitamin D deficiency during pregnancy affects the child's lung function predisposition towards lung disease such as asthma.
Research
A prospective audit of pain profiles following general and urological surgery in childrenTo determine the duration and severity of acute postoperative pain experienced by children undergoing 8 different general and urological procedures.
Research
The impact of respiratory viruses on lung health after preterm birthThe aim of this review is to highlight the risk factors that may contribute to increased susceptibility to viral respiratory infections among preterm infants
Research
Perception of pediatric pain: A comparison of postoperative pain assessments between child, parent, nurse, and independent observerDifferences in the assessment of pediatric pain between children, parents, nurses, and independent observers in the acute postoperative setting