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Research

Aberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumours

The class 1A aldehyde dehydrogenase (ALDH1A) subfamily of genes encode enzymes that function at the apex of the retinoic acid (RA) signalling pathway.

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Olfactory identification deficits at identification as ultra-high risk for psychosis are associated with poor functional outcome

We have previously reported that olfactory identification (OI) deficits are a promising premorbid marker of transition from ultra-high risk...

Research

Use of the ketogenic diet to manage refractory epilepsy in CDKL5 disorder

In view of its side effect profile, ketogenic diet (KD) administration should be supervised by a pediatric neurologist and specialist dietician.

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Parental perspectives on the communication abilities of their daughters with Rett syndrome

How females with Rett syndrome communicate in everyday life and the barriers and facilitators to successful communication

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A Retrospective case-series of children with bone and joint infection from northern Australia

We report osteomyelitis incidence in indigenous children of northern Australia is amongst the highest reported in the world

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Chronic illness and developmental vulnerability at school entry

Chronic illness in young children is a risk factor for reduced school readiness

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Risk factors for repetition of a deliberate self-harm episode within seven days in adolescents and young adults

The risk of repetition of deliberate self-harm peaks in the first 7 days after a deliberate self-harm episode.

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Rapid recruitment of CD14+ monocytes in experimentally induced allergic rhinitis in human subjects

Mononuclear phagocyte population is directly involved in the production of proinflammatory chemokines that attract other immune cells

Research

Adverse metabolic phenotype of adolescent girls with non-alcoholic fatty liver disease plus polycystic ovary syndrome compared with other girls and boys

Non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) share risk associations of adiposity and insulin resistance.