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Research

Exercise alone reduces insulin resistance in obese children independently of changes in body composition

The number of obese children with insulin resistance and type 2 diabetes is increasing, but the best management strategy is not clear.

Research

A DTPa-HBV-IPV vaccine for primary vaccination of infants

Combined vaccines have an increasingly important role to play in delivering these antigens acceptably.

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Reduced levels of antimicrobial proteins and peptides in human cord blood plasma

Reduced levels of antimicrobial proteins and peptides in human cord blood plasma.

Research

Polymorphisms in key innate immune genes and their effects on measles vaccine responses and vaccine failure in children from Mozambique

Despite an effective vaccine, measles remains a major health problem globally, particularly in developing countries. More than 30% of children show primary...

Research

The effect of short-term use of the Guardian RT continuous glucose monitoring system on fear of hypoglycaemia in patients with type 1 diabetes mellitus

This study examines whether the short-term use of a continuous glucose monitor can reduce the fear of hypoglycaemia in individuals with type 1 diabetes...

Research

Safety, immunogenicity, and tolerability of meningococcal serogroup B bivalent recombinant lipoprotein 2086 vaccine in healthy

Neisseria meningitidis serogroup B is a major cause of invasive meningococcal disease, but a broadly protective vaccine is not currently licensed. A bivalent...

Research

No dose-dependent increase in fracture risk after long-term exposure to high doses of retinol or beta-carotene

This intervention study found no increase in fracture risk among 2,322 adults who took a controlled, high-dose retinol supplement for as long as 16 years.

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A molecular dynamics study of C1r and C1s dimers: Implications for the structure of the C1 complex

Complement is an important part of the immune system. It is initiated through three different pathways known as the classical, lectin, and alternative pathway.

Research

Father mental health during the early parenting period: results of an Australian population based longitudinal study

The primary objective of this study was to report on the occurrence of mental health difficulties for a large national sample of Australian fathers of children.