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A community-led, trauma-informed psychosocial intervention to improve health outcomes of children and young people with Type-1 diabetes

T1D can be a traumatic diagnosis for children and young people, and often involves strict adherence to painful treatments, comorbid mental health conditions, and shortened life expectancy.

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A validation study of a modified Bouchard activity record that extends the concept of 'uptime' to Rett syndrome

The aim of this study was to investigate the validity of using a Bouchard activity record (BAR) in individuals with Rett syndrome to measure physical...

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Novel peptide-based drugs for the treatment of sonic hedgehog-dependent medulloblastoma

Medulloblastoma, the most common pediatric malignant brain tumor, consists of at least four distinct molecular subgroups.

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Controlling acute rheumatic fever and rheumatic heart disease in developing countries: Are we getting closer?

Improved opportunities for the primary prevention of ARF now exist, because of point-of-care antigen tests for Streptococcus pyogenes, and clinical decision...

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Onset of maternal psychiatric disorders after the birth of a child with intellectual disability: A retrospective cohort study

Mothers of a child with intellectual disability (ID) have more psychiatric disorders after the birth of their child than other mothers.

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Plasma micronutrient levels and telomere length in children

Telomeres are long hexamer (TTAGGG) repeats at the ends of chromosomes, and contribute to maintenance of chromosomal stability.

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Childhood behavior problems and age at first sexual intercourse: A prospective birth cohort study

Early first sexual intercourse (FSI) is a risk factor for unplanned abstract teenage pregnancy, sexually transmitted infection, and adverse social, emotional...

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The effect of weight management interventions that include a diet component on weight related outcomes in pregnant and postpartum women

The effects of weight management interventions that include a diet component on weight-related outcomes in pregnant and postpartum women.

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Post hoc analysis of the PATRICIA randomized trial of the efficacy of human papillomavirus type 16 (HPV-16)/HPV-18 AS04-adjuvanted vaccine

The efficacy of the human papillomavirus type 16 (HPV-16)/HPV-18 AS04-adjuvanted vaccine against cervical infections with HPV...

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The 'Can't Intubate Can't Oxygenate' scenario in pediatric anesthesia: A comparison of the Melker cricothyroidotomy kit with a scalpel bougie technique

While the majority of pediatric intubations are uncomplicated, the 'Can't intubate, Can't Oxygenate' scenario (CICO) does occur.