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Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cellsMature B cells, CR2/CD21 transcription proceeds from a focused TSS regulated by a non-consensus TATA box, an initiator element and downstream promoter element
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Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinentOur results reveal the complexity of Leishmania donovani evolution in the Indian subcontinent in response to drug treatment
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Novel peptide-based drugs for the treatment of sonic hedgehog-dependent medulloblastomaMedulloblastoma, the most common pediatric malignant brain tumor, consists of at least four distinct molecular subgroups.
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Onset of maternal psychiatric disorders after the birth of a child with intellectual disability: A retrospective cohort studyMothers of a child with intellectual disability (ID) have more psychiatric disorders after the birth of their child than other mothers.
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Controlling acute rheumatic fever and rheumatic heart disease in developing countries: Are we getting closer?Improved opportunities for the primary prevention of ARF now exist, because of point-of-care antigen tests for Streptococcus pyogenes, and clinical decision...
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Environmental health challenges in remote Aboriginal Australian communities: clean air, clean water and safe housingA considerable health disparity exists between Aboriginal and non-Aboriginal Australians, including a higher incidence and severity of cardiovascular and...
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Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cellsOur data support a highly generalizable model in which enhancer transcription is the earliest event in successive waves of transcriptional change during...
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Childhood behavior problems and age at first sexual intercourse: A prospective birth cohort studyEarly first sexual intercourse (FSI) is a risk factor for unplanned abstract teenage pregnancy, sexually transmitted infection, and adverse social, emotional...
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Genetic and environmental factors in the aetiology of hypospadiasThe increasing use of assisted reproductive techniques and hormonal manipulation during pregnancy may have been associated with an apparent rise in the...
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The effect of weight management interventions that include a diet component on weight related outcomes in pregnant and postpartum womenThe effects of weight management interventions that include a diet component on weight-related outcomes in pregnant and postpartum women.