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Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEPOur results suggest that intracellular infection with the pathogenic GAS M1T1 clone induces a strong pro-inflammatory response in primary tonsil epithelial cells
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Comparable glycemic outcomes for pediatric type 1 diabetes patients in metropolitan and non-metropolitan regions of Western Australia: A population-based studyThis study reports similar glycemic outcomes for patients attending diabetes clinics in metropolitan and non-metropolitan areas of WA
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Effects of Dietary Acute Tryptophan Depletion (ATD) on NPY Serum Levels in Healthy Adult Humans Whilst Controlling for Methionine Supply-A Pilot StudyAcute tryptophan depletion, and therefore, diminished substrate availability for brain 5-HT synthesis did not lead to significant changes in serum neuropeptide Y concentrations over time
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Independent and combined effects of airway remodelling and allergy on airway responsivenessThere was a positive relationship between the thickness of the airway smooth muscle layer with airway responsiveness, which was shifted upward in the presence of allergy
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Defining relevant hypoglycemia measures in children and adolescents with type 1 diabetesAs the choices of therapies in diabetes care multiply, it is essential to standardize the approach to measuring and recording hypoglycemia risk
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Determinants of a dietary pattern linked with greater metabolic risk and its tracking during adolescenceAlthough growing evidence suggests that dietary patterns associated with noncommunicable disease in adulthood may develop early in life.
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Conserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuliWe obtain a set of 57 candidate immediate early genes possessing promoters that consistently drive a rapid but transient increase in expression over time
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Associations between proposed local government liquor store size classifications and alcohol consumption in young adultsYoung adults' alcohol consumption appears to be impacted by liquor store density and convenience, rather than outlet size
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Performance of medtronic hybrid closed-loop iterations: Results from a randomized trial in adolescents with type 1 diabetesThis study investigates the performance of an iteration of the Medtronic hybrid closed-loop algorithm
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CrossTalk opposing view: Mucosal acidification does not drive early progressive lung disease in cystic fibrosisWhether airway mucosal acidification drives early progressive lung disease is controversial