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Research

Humidified high-flow nasal cannula oxygen for bronchiolitis: Should we go with the flow?

Current NICE 2015 guidelines for bronchiolitis state that the use of HFNC is becoming widespread without demonstration of additional efficacy.

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School readiness of maltreated children: Associations of timing, type, and chronicity of maltreatment

In this study, the Australian Early Development Census scores of 19,203 children were linked to information on child maltreatment allegations.

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Fragranced consumer products: effects on asthmatic Australians

Most asthmatics would prefer workplaces, healthcare facilities, and environments that are fragrance-free, which could help reduce adverse effects

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Reduction in hypoglycemia with the predictive low-Glucose management system: A long-term randomized controlled trial in adolescents with type 1 diabetes

Short-term studies with automated systems that suspend insulin when hypoglycemia is predicted have shown a reduction, but safety and efficacy aren't established

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Pre-onset risk characteristics for mania among young people at clinical high risk for psychosis

We aimed to identify the rate and predictors of transition to mania in a cohort of youth with clinical or familial risk for psychosis.

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Implications of asymptomatic carriers for infectious disease transmission and control

For pathogens such as Staph. A and Streptococcus P., some hosts may carry the pathogen and transmit it to others, yet display no symptoms themselves.

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Diffuse Intrinsic Pontine Glioma

This chapter summarizes recent advances in diffuse intrinsic pontine glioma and potential novel therapies

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Insulin Pump Therapy in Adolescents With Very Poor Glycemic Control During a 12-Month Cohort Trial

We conclude that insulin pump therapy can be an effective tool to improve glycemic control in adolescents with long-standing treatment resistance

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Conserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuli

We obtain a set of 57 candidate immediate early genes possessing promoters that consistently drive a rapid but transient increase in expression over time

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Performance of medtronic hybrid closed-loop iterations: Results from a randomized trial in adolescents with type 1 diabetes

This study investigates the performance of an iteration of the Medtronic hybrid closed-loop algorithm