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Examining the overlap between genes perturbed in the KD-CAGE experiments and genes with a ChIP-seq peak within 50 kb of their promoter, we identified direct...
Our data support a highly generalizable model in which enhancer transcription is the earliest event in successive waves of transcriptional change during...
The immediate-early response mediates cell fate in response to a variety of extracellular stimuli and is dysregulated in many cancers.
The generation of myeloid cells from their progenitors is regulated at the level of transcription by combinatorial control of key transcription factors...
The FANTOM5 project investigates transcription initiation activities in more than 1,000 human and mouse primary cells, cell lines and tissues using CAGE.
Arguably the most basic step in the analysis of next generation sequencing data (NGS) involves the extraction of mappable reads from the raw reads...
This study reports that telomerase reverse transcriptase extensively affects the expression levels of mature microRNAs.
A systematic comparison of the cellular and molecular changes in neurons in vitro induced by low intensity magnetic stimulation at different frequencies.
To investigate the effect of interpregnancy interval (IPI) on preterm birth (PTB) according to whether the previous birth was preterm or term.
Systematic comparison of recovered cell types and their transcriptional profiles across the workflows has highlighted protocol-specific biase