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Gene regulation by 1,25-dihydroxyvitamin D3 in CD4+CD25+ cells is enabled by IL-2

Vitamin D may be responsible for reducing the development and severity of autoimmune and allergic diseases. Topically applied 1,25-dihydroxyvitamin D(3) (1,25(O

Immune-modifying properties of topical vitamin D: Focus on dendritic cells and T cells

Topical creams containing the active form of vitamin D (1,25-dihydroxyvitamin D3; 1,25(OH)2D3) or analogues of this compound are currently used with some succes

UV inhibits allergic airways disease in mice by reducing effector CD4 T cells

In human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4

Time spent outdoors through childhood and adolescence - assessed by 25-hydroxyvitamin D concentration - and risk of myopia at 20 years

To investigate the relationship between time spent outdoors, at particular ages in childhood and adolescence, and myopia status in young adulthood using serum 25-hydroxyvitamin D [25(OH)D] concentration as a biomarker of time spent outdoors. Participants of the Raine Study Generation 2 cohort had 25(OH)D concentrations measured at the 6-, 14-, 17- and 20-year follow-ups. Participants underwent cycloplegic autorefraction at age 20 years, and myopia was defined as a mean spherical equivalent -0.50 dioptres or more myopic. Logistic regression was used to analyse the association between risk of myopia at age 20 years and age-specific 25(OH)D concentrations. Linear mixed-effects models were used to analyse trajectory of 25(OH)D concentrations from 6 to 20 years.

Government funding for innovative sun safety online tool for teens

The Kids researcher Dr Shelley Gorman has received a Healthway grant to develop an online tool to promote safe sun behaviours to teenagers.

UV and Vitamin D

Researchers at The Kids Research Institute Australia are continuing to hone in on the effects of ultraviolet radiation and vitamin D on the immune system.

Sun safe: balancing the risks and benefits

The D-Light program, set up in 2014, aims to shed light on the amount of sun exposure that will promote good health in children and adolescents.

Research symposium to hear how sunscreens proved no threat to vitamin D production in recent European study

Leading international and national experts will gather at The Kids Research Institute Australia on Friday for a D-Light Research Symposium.

Vitamin D link to depression in mothers

Research by The Kids Research Institute Australia shows a link between low vitamin D during pregnancy and post-natal depression.