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Research

Innate Immune Training for Prevention of Recurrent Wheeze in Early Childhood

Pat Deborah Holt Strickland PhD, DSc, FRCPath, FRCPI, FAA PhD Emeritus Honorary Researcher Head, Pregnancy and Early Life Immunology Patrick.Holt@

Research

The cellular effects of estrogen on allergic asthma

The study aims to identify the mechanism for this so that this knowledge can be used to better treat asthma and allergies in both males and females.

Research

Mechanisms of IgE sensitization

This project investigates how cells of the immune system respond to substances to cause allergies to help develop new treatments.

Research

World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Vitamin D

Vitamin D is involved in the regulation of the immune system and it may play a role in the development, severity and course of asthma and other allergic...

Research

Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma

In this study, we aimed to use microRNAs-which are critical regulators of signaling cascades-to identify so far uncharacterized asthma pathogenesis pathways

Research

Relationship between cytokine expression patterns and clinical outcomes: two population-based birth cohorts

Our findings suggest that positive HDM 'allergy tests' and asthma are associated with a broad range of immunophenotypes, which may have important...

Research

Reversible Control by Vitamin D of Granulocytes and Bacteria in the Lungs of Mice: An Ovalbumin-Induced Model of Allergic Airway Disease

Vitamin D may be essential for restricting the development and severity of allergic diseases and asthma, but a direct causal link between vitamin D...

News & Events

New lease on life for Dartanyon

Two years on, Michelle and Dartanyon’s health and quality of life have significantly improved. We caught up with Michelle to hear about their journey since we first met them.

News & Events

Call for mental health support for kids with asthma

A new study has found that young children with severe or persistent asthma are at higher risk of developing many common mental health problems.