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Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothersWe sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception.
Research
Associations of Early- and Later-Childhood Poverty with Child Cognitive Function in Indonesia: Effect Decomposition in the Presence of Exposure-Induced Mediator-Outcome ConfoundingOur analysis shows that early and late intervention to support household income have equal importance with regards to significance of impact.
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Phylomer Libraries: A Rich Source of Peptide Hits in Phenotypic and Target Directed ScreensThe poor hit rates associated with conventional random peptide libraries present formidable challenges in genetic screening formats with limited throughput.
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Structure-diverse Phylomer libraries as a rich source of bioactive hits from phenotypic and target directed screens against intracellular proteinsPhylomer libraries are being increasingly used in applications such as phenotypic screening where the numbers of peptides which can be feasibly screened is limited
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ANRIL Promoter DNA Methylation: A Perinatal Marker for Later AdiposityExperimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes.
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Associations between school absence and academic achievement: Do socioeconomics matter?School attendance should therefore be a priority for all schools, and not just those with high rates of absence or low average achievement.
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A Retrospective case-series of children with bone and joint infection from northern AustraliaWe report osteomyelitis incidence in indigenous children of northern Australia is amongst the highest reported in the world
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A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control StudiesThese results highlight how UNICORN can enable reliable, powerful, and convenient genetic association analyses without access to the individual-level data
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Status of research and development of vaccines for Streptococcus pyogenesVaccines against Streptococcus pyogenes are considered as impeded vaccines because of a number of crucial barriers to development
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Short report: Relationship between restricted and repetitive behaviours in children with autism spectrum disorder and their parentsRestricted and repetitive behaviours constitute a core symptom domain of autism spectrum disorder