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Research

Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990-2015: findings from the Global Burden of Disease 2015 study

The age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average.

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Population-based estimates of the effectiveness of pneumococcal vaccination in Australia

Australia’s Childhood Immunisation Register (ACIR) is one of only a handful of national immunisation registers world-wide.

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Randomized controlled trial of early regular egg intake to prevent egg allergy

We aimed to determine whether regular consumption of egg protein from 4-6 month old reduced the risk of IgE-mediated egg allergy in infants without eczema.

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Repeated vaccination does not appear to impact upon influenza vaccine effectiveness against hospitalization with confirmed influenza

These findings reinforce current recommendations for annual influenza vaccination, particularly those at greatest risk of influenza disease.

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Latent Class Analysis of Neurodevelopmental Deficit After Exposure to Anesthesia in Early Childhood

Some studies suggest an association between early exposure to anesthesia, surgery and long term developmental deficit, clinical phenotype of children is unknown

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The effects of electronic cigarette aerosol exposure on inflammation and lung function in mice

This study shows, for the first time, that exposure to e-cigarette aerosol during adolescence and early adulthood is not harmless to the lungs and can result in significant impairments in lung function.

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Associations of Early- and Later-Childhood Poverty with Child Cognitive Function in Indonesia: Effect Decomposition in the Presence of Exposure-Induced Mediator-Outcome Confounding

Our analysis shows that early and late intervention to support household income have equal importance with regards to significance of impact.

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Structure-diverse Phylomer libraries as a rich source of bioactive hits from phenotypic and target directed screens against intracellular proteins

Phylomer libraries are being increasingly used in applications such as phenotypic screening where the numbers of peptides which can be feasibly screened is limited

Research

ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

Experimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes.