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Research

Research opportunities for the primordial prevention of rheumatic fever and rheumatic heart disease - streptococcal vaccine development: a national heart, lung and blood institute workshop report

Streptococcus pyogenes, also known as group A streptococcus (StrepA), is a bacterium that causes a range of human diseases, including pharyngitis, impetigo, invasive infections, and post-infection immune sequelae such as rheumatic fever and rheumatic heart disease. StrepA infections cause some of the highest burden of disease and death in mostly young populations in low-resource settings. Despite decades of effort, there is still no licensed StrepA vaccine, which if developed, could be a cost-effective way to reduce the incidence of disease. 

Research

Verschlimmbesserung: Craniospinal Radiotherapy Is Essential in WNT Medulloblastoma Patients

Standard-risk WNT medulloblastoma patients have an excellent prognosis using the combination of standard dose craniospinal radiotherapy (CSI) followed by platinum and alkylator based chemotherapy. A recent pilot study that attempted to completely omit radiotherapy was terminated early as all patients relapsed rapidly. The study highlights that therapy is the most important prognostic factor, with CSI still required to cure even the most favorable subgroup of medulloblastoma patients. 

Research

Novel intranasal phage-CaEDTA-ceftazidime/avibactam triple combination therapy demonstrates remarkable efficacy in treating Pseudomonas aeruginosa lung infection

Given the rise of multidrug-resistant (MDR) Pseudomonas aeruginosa infections, alternative treatments are needed. Anti-pseudomonal phage therapy shows promise, but its clinical application is limited due to the development of resistance and a lack of biofilm penetration. 

Research

Outcomes following intensive day rehabilitation for young people in Western Australia

Intensive rehabilitation aims to improve and maintain functioning in young people who experience disability due to illness or injury. Day rehabilitation may have advantages for families and healthcare systems over inpatient models of rehabilitation. 

People Power

One of Australia’s leading cancer research centres continues to be powered by parents who decided to fight back. Hard.

Telethon celebrates 50 years of raising funds and awareness

Maddox Ball and The Kids researcher Dr Ingrid Laing might not look like they have a lot in common but they share a very special bond.

Achieving lasting change in the Kimberley

Many people would be daunted when tasked with coordinating, from scratch, a new The Kids Research Institute Australia satellite site to service WA’s north. But not John Jacky

News & Events

Decades of bullying research pays off

Professor Donna Cross and her team at The Kids Research Institute Australia have challenged and overturned damaging attitudes that saw bullying tolerated in childhood.

News & Events

$1.2million in funding secured for two innovative projects

The Kids researchers are collaborating on two major projects that today received $1.2million in funding from MTPConnect.

News & Events

The Kids Kimberley: Researchers and communities working together

In 2016, with enabling donations from Denby Roberts, Stan Perron, Wesfarmers and Centurion, the Institute established a permanent presence in the Kimberley.