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This study is designed to identify the specific unique immune cell response that occurs in these children with recurrent disease.
Studies in Europe show exposure of pregnant women to high levels of microbial products stimulate immune function maturation in their offspring
The study aims to identify the mechanism for this so that this knowledge can be used to better treat asthma and allergies in both males and females.
This project investigates how cells of the immune system respond to substances to cause allergies to help develop new treatments.
This work is the first step to develop safe treatments for pregnant mums to protect against preterm delivery and low birth weight caused by maternal infections.
This study identified that expsoure to folate has effects on the regulation of DNA methylation during fetal development.
The complement system plays a major role in the autoimmune disease, systemic lupus erythematosus (SLE). This review highlights the many roles of complement for
One explanation for the high burden of allergic and autoimmune diseases in industrialized countries is inappropriate immune development under modern...
Remission is the desired outcome following OIT as it allows individuals to discontinue treatment and eat the allergen freely. Early initiation of OIT in infants and toddlers has been embraced as an approach to increase the likelihood of remission. However, there is no high-quality evidence supporting younger age as an independent factor driving remission; available studies are limited by small samples of younger subjects and lack of adjustment for confounding covariates, particularly peanut-specific IgE (sIgE) levels which is closely cor
Few studies have examined long-term outcomes following oral immunotherapy; none have examined long-term risks and benefits associated with distinct clinical outcomes (desensitization, remission).