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Frankenstein Cas9: engineering improved gene editing systemsThe discovery of CRISPR-Cas9 and its widespread use has revolutionised and propelled research in biological sciences.
Research
Healthy Environments and Lives (HEAL): Australian research network in human health and environmental changeThe HEAL Network aims to strengthen the Australian health system and community resilience to climate change, extreme events, and environmental degradation.
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The health-related quality of life of lung cancer patients with EGFR-The Kids-related skin adverse drug reactions and its relationship with coping style and self-managementThe status and associated factors of the health-related quality of life of non-small-cell lung cancer patients under targeted anti-cancer therapy have not been investigated. Self-management and coping style have been proven to be closely related to patients’ health-related quality of life.
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Molecular Mechanisms and Applications of N-Acyl Homoserine Lactone-Mediated Quorum Sensing in BacteriaMicrobial biodiversity includes biotic and abiotic components that support all life forms by adapting to environmental conditions. Climate change, pollution, human activity, and natural calamities affect microbial biodiversity.
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Probiotic supplementation in neonates with congenital gastrointestinal surgical conditions: a pilot randomised controlled trialTo evaluate whether probiotic supplementation attenuates gut-dysbiosis in neonates with congenital gastrointestinal surgical conditions.
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Celebrating the lived experience of socio-economic disadvantage in the public health workforceCitation: Mandzufas J. Celebrating the lived experience of socio-economic disadvantage in the public health workforce. Health Promot J Austr. 2022;33
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Diagnosis and analysis of unexplained cases of childhood encephalitis in Australia using metatranscriptomic sequencingEncephalitis is most often caused by a variety of infectious agents identified through diagnostic tests utilizing cerebrospinal fluid. We investigated the clinical characteristics and potential aetiological agents of unexplained encephalitis through metagenomic sequencing of residual clinical samples from multiple tissue types and independent clinical review.
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Is early childhood development impeded by the birth timing of the younger sibling?This study investigated whether the timing of birth of the younger siblings was associated with the risk of the older siblings’ developmental vulnerability in early childhood.
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Short- versus standard-course intravenous antibiotics for peri-prosthetic joint infections managed with debridement and implant retention: a randomised pilot trial using a desirability of outcome ranking (DOOR) endpointPeri-prosthetic joint infection (PJI) is a devastating complication of joint replacement surgery. Determining the optimal duration of intravenous (IV) antibiotics for PJI managed with debridement and implant retention (DAIR) is a research priority.
Research
A novel statistical framework for exploring the population dynamics and seasonality of mosquito populationsUnderstanding the temporal dynamics of mosquito populations underlying vector-borne disease transmission is key to optimizing control strategies. Many questions remain surrounding the drivers of these dynamics and how they vary between species-questions rarely answerable from individual entomological studies (that typically focus on a single location or species).