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Physical activity participation among children diagnosed with mental health disorders: A qualitative analysis of children’s and their guardian’s perspectivesChildren with mental health disorders have lower physical activity levels compared to their peers; however, minimal research has been conducted to date to understand their unique experiences of physical activity. We sought to better understand these experiences, along with contributing factors, through interviews with children with mental health disorders and their parents/guardians.
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A Methylome and Transcriptome Analysis of Normal Human Scar Cells Reveals a Role for FOXF2 in Scar MaintenanceScars are maintained for life and increase in size during periods of growth such as puberty. Epigenetic changes in fibroblasts after injury may underpin the maintenance and growth of scars. In this study, we combined methylome and transcriptome data from normotrophic mature scar and contralateral uninjured normal skin fibroblasts to identify potential regulators of scar maintenance.
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ATAGI 2021 annual statement on immunisation Last updated: 19 September 2021Christopher Blyth MBBS (Hons) DCH FRACP FRCPA PhD Centre Head, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases
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Defining the fetal origin of MLL-AF4 infant leukemia highlights specific fatty acid requirementsInfant MLL-AF4-driven acute lymphoblastic leukemia (ALL) is a devastating disease with dismal prognosis. A lack of understanding of the unique biology of this disease, particularly its prenatal origin, has hindered improvement of survival. We perform multiple RNA sequencing experiments on fetal, neonatal, and adult hematopoietic stem and progenitor cells from human and mouse.
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Achieving universal electrification of rural healthcare facilities in sub-Saharan Africa with decentralized renewable energy technologiesA potential response to the COVID-19 pandemic in sub-Saharan Africa (SSA) with long-term benefits is to provide electricity for medical equipment in rural health centers and communities. This study identifies a large gap in the electrification of healthcare facilities in SSA, and it shows that decentralized photovoltaic systems can offer a clean, reliable, quick, and cost-effective solution.
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Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trialProtracted bacterial bronchitis (PBB) is a leading cause of chronic wet cough in children. The current standard treatment in European and American guidelines is 2 weeks of antibiotics, but the optimal duration of therapy is unknown. We describe the first randomised controlled trial to assess the duration of antibiotic treatment in children with chronic wet cough and suspected PBB.
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Leading excellence through equity: Social emotional learning for a Fair GoAustralia likes to call itself the land of the "Fair Go". But what does a Fair Go mean for students from backgrounds of deep disadvantage? The UN Sustainable Development Goals for 2030 aim to ensure "inclusive and equitable quality education and [to promote] lifelong learning opportunities for all" (United Nations, 2015).
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People with Cerebral Palsy and Their Family's Preferences about Genomics ResearchThe goal of this study was to understand individuals with cerebral palsy (CP) and their family's attitudes and preferences to genomic research, including international data sharing and biobanking.
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Microcephaly in Australian infants: A retrospective auditThe aim of this study was to describe clinical characteristics, outcomes and causes of microcephaly in children whose condition was identified within the first year of life.
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Reflections on How Tinnitus Impacts the Lives of Children and AdolescentsThe aim of this study was to generate a conceptual framework describing which aspects of children and adolescents' lives are affected by chronic tinnitus.