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Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsinPresent a valuable resource for drug discovery and have identified ROM as a promising therapeutic for MLL-rearranged iALL
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The rare and undiagnosed diseases diagnostic service – application of massively parallel sequencing in a state-wide clinical serviceThe Rare and Undiagnosed Diseases Diagnostic Service refers to a genomic diagnostic platform operating within the Genetic Services of Western Australia
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Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studiesPregnancy and birth cohorts have been utilised extensively to investigate the developmental origins of health and disease, particularly in relation to...
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Grow up with your countryThis commentary discusses the keys to empowering individuals & families to navigate the health, education, employment & social systems & to access relevant...
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Defining the appropriate waiting time between multiple-breath nitrogen washout measurementsThis letter addresses the recommendations by the American Thoracic Society & European Respiratory Society in 2005, that patients must wait 15-60mins between...
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Respiratory toxicology of e-cigarettes: effect of vapours on lung function and inflammationElectronic cigarettes (ECs) have been rapidly gaining ground on conventional cigarettes due to their efficiency in ceasing or reducing tobacco consumption,...
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Outcomes of nontransitioned cases in a sample at ultra-high risk for psychosis.Two-thirds of individuals identified as at ultra-high risk for psychosis do not develop psychotic disorder over the medium term.
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Lung function and exhaled nitric oxide in healthy unsedated African infantsPopulation-appropriate lung function reference data are essential to accurately identify respiratory disease and measure response to interventions.
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Ahead of consensus: A paediatric antifungal prophylaxis censusTo contextualise the ‘Australian & New Zealand Antifungal Consensus Guidelines, 2014, researchers surveyed current routine primary antifungal prophylaxis.
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Influenza vaccine effectiveness and uptake in children at risk of severe diseaseParticipation in the preschool influenza vaccination program remains low with parents unconvinced of the benefits and safety of influenza vaccine