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Research

LPS binding protein and activation signatures are upregulated during asthma exacerbations in children

Asthma exacerbations in children are associated with respiratory viral infection and atopy, resulting in systemic immune activation and infiltration of immune cells into the airways. The gene networks driving the immune activation and subsequent migration of immune cells into the airways remains incompletely understood. Cellular and molecular profiling of PBMC was employed on paired samples obtained from atopic asthmatic children during acute virus-associated exacerbations and later during convalescence.

Research

Priority setting for children and young people with chronic conditions and disabilities

The aim of this project was to identify the top 10 priorities for childhood chronic conditions and disability (CCD) research from the perspectives of children and young people with lived experience, their parents and caregivers and the professionals who work with them.

Research

Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profiles

the association between infant LRTI and risk for persistent wheeze/asthma in this cohort is generally stronger for fLRTIs than for other infection categories

News & Events

Bold bid to end rheumatic heart disease

Some of the nation’s leading medical researchers will converge on Darwin this week to step out a plan to wipe out rheumatic heart disease.

Research

Activated Outside School Hours Care (OSHC)

Hayley Karen Christian Lombardi BSc (1st Class Hons), PhD W.Aust. BHSc (Hons), PhD Program Head, Healthy Behaviours and Environments; National Heart

Research

Training Service Providers to work with Aboriginal and Torres Strait Islander LGBTQA+ youth

Bep Shakara Mirella Uink Liddelow-Hunt Wilson BPsych(Hons.), MAppPsy(Clinical), PhD BPhil(Hons) MAppPsych(Organisational), BA(Hons.) Honorary

Research

Using Systems Biology to understand asthma exacerbations and develop better treatments

Alexander Anthony Deborah Emma Pat Larcombe Kicic Strickland de Jong Holt BScEnv (Hons) PhD BSc (Hons) PhD PhD PhD, DSc, FRCPath, FRCPI, FAA Honorary

Research

What is triggering immune reactions in people with MS?

Multiple sclerosis (MS) is a condition where a person's immune system attacks the brain and spinal cord.