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Associations Between Hyperphagia, Symptoms of Sleep Breathing Disorder, Behaviour Difficulties and Caregiver Well-Being in Prader-Willi Syndrome: A Preliminary StudyPrader-Willi syndrome (PWS) is a rare genetic disorder characterised by neurodevelopmental delays, hyperphagia, difficulties with social communication and challenging behaviours. Individuals require intensive supervision from caregivers which may negatively affect caregiver quality of life. This study used data collected in the Australasian PWS Registry to evaluate associations between child behaviours and caregiver mental well-being.
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Diverse Anti-Tumor Immune Potential Driven by Individual IFNα SubtypesOur data shows that the expression of distinct IFNα subtypes within the tumor microenvironment results in different anti-tumor activities
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Relationship Between Social Motivation in Children With Autism Spectrum Disorder and Their ParentsImpairment in social motivation (SM) has been suggested as a key mechanism underlying social communication deficits observed in autism spectrum disorder (ASD). However, the factors accounting for variability in SM remain poorly described and understood. The current study aimed to characterize the relationship between parental and proband SM. Data from 2,759 children with ASD and their parents from the Simons Simplex Collection (SSC) project was included in this study.
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Evaluation of an Australian neurological nurse-led model of postdischarge careNeurological disorders are a leading cause of disease burden worldwide, placing a heavy demand on health systems. This study evaluated the impacts and cost savings of a community-based nursing service providing supported discharge for neurological patients deemed high-risk for unplanned emergency department presentations and/or hospital readmissions. It focused on adult patients with stroke, epilepsy, migraine/headache or functional neurological disorders discharged from a Western Australian tertiary hospital.
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Continuous Glucose Monitoring Adherence: Lessons from a Clinical Trial to Predict Outpatient BehaviorContinuous glucose monitoring adherence and patterns of use are individualized
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A novel clinical prediction model for prognosis in malignant pleural mesothelioma using decision tree analysisA simple, clinically relevant model to reliably discriminate patients at high and lower risk of death in patients with malignant pleural mesothelioma
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Risk factors for malignant mesothelioma in people with no known exposure to asbestosThis study aimed to identify sources whereby people in Western Australia (WA) may be unknowingly exposed to asbestos or to other exposures which may cause MM.
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Estimation of quantitative levels of diesel exhaust exposure and the health impact in the contemporary Australian mining industryTo estimate the levels of exposure to diesel exhaust expressed by EC in the mining industry and to describe the risk of lung cancer that may result from it.
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Limited impact of neonatal or early infant schedules of 7-valent pneumococcal conjugate vaccinationEarly 7vPCV schedules have limited impact on pneumococcal vaccine type carriage in PNG
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Establishing a process for conducting cross-jurisdictional record linkage in AustraliaWe outline the processes involved in conducting a Proof of Concept data linkage project including the implementation of national data integration principles