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Pre-clinical models that effectively recapitulate human disease are critical for expanding our knowledge of cancer biology and drug resistance mechanisms.
Aberrant expression of the TLX1/HOX11 proto-oncogene is associated with a significant subset of T-cell acute lymphoblastic leukemias...
CD8α+ DCs are not the sole subset cross-presenting cell associated tumor antigens from a solid tumor
We examined the baseline profile of a panel of T-ALL cell lines to determine factors that contribute to GC resistance without prior drug selection.
In this investigation, the authors found an association between home pesticide exposure before birth and during a child's early years and acute lymphoblastic...
This paper demonstrated that home paint exposure shortly before conception, during pregnancy, and/or after birth appeared to increase the risk of childhood ALL.
This report provides new insight into the functional specialization within the broad network of dendritic cells that are responsible for skin immunosurveillance
This article summarizes data from collaborative group and institutional trials that have advanced the science of pediatric brain tumors.
We undertook a retrospective review of children diagnosed with acute lymphoblastic leukemia (ALL) and treated with modern COG protocols to determine...
This article investigates the impact of burn & excisional injury on the immune system.