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Research

Net Promoter Score Model for Evaluating Paediatric Medicine Acceptability: Validation and Feasibility Study

Medicine acceptability is crucial for paediatric drug development, yet its assessment remains challenging due to the multifaceted nature of sensory attributes like taste, smell, and mouthfeel. Traditional methods of acceptability evaluation often involve complex questionnaires and lack standardisation, leading to difficulties in a comparative analysis across studies.

Research

4CMenB Breadth of Immune Response, Immunogenicity, and Safety: Results from a Phase 3 Randomized, Controlled, Observer Blind Study in Adolescents and Young Adults

Meningococcal serogroup B (MenB) strains are highly diverse. Breadth of immune response for the MenB vaccine, 4CMenB, administered at 0-2, 0-6, or 0-2-6 months, was demonstrated by endogenous complement-human serum bactericidal antibody (enc-hSBA) assay against an epidemiologically relevant panel of 110 MenB strains.

News & Events

Churchlands High School Fun Run hits $30,000

Over 1000 Year 7 and 8 students from Churchlands Senior High School laced up their running shoes yesterday for their annual Fun Run raising money for the Wesfarmers Centre of Vaccines and Infectious Diseases.

News & Events

The Kids ‘Tall Poppies’ rise above the rest

Three The Kids researchers have been named amongst WA’s most outstanding young scientists for their efforts to ensure kids around the country have the chance to lead happy and healthy lives.

News & Events

New ear health study music to the ears of Aboriginal children

Wait times for Aboriginal children suffering ear infections could be reduced to less than four weeks thanks to a new The Kids Research Institute Australia research project

News & Events

$3.4mill to improve treatment management of cystic fibrosis

The Kids researchers have been awarded over $3.4 million for a new trial to pioneer improved ways for managing cystic fibrosis (‘CF’).

News & Events

Bill & Melinda Gates Foundation Grant aims to prevent deadly infections in early life

Newborn babies and their fragile immune systems struggle to fight off nasty infections such as septicaemia, pneumonia and gastroenteritis.

News & Events

The Kids Research Institute Australia researcher recognised for saving children in PNG

Clinical Associate Professor Deborah Lehmann has been recognised for her dedication to reducing the burden of infectious diseases in Papua New Guinea (PNG) with an award supporting research in the Western Pacific named in her honour.

Research

Does adjunctive clindamycin have a role in Staphylococcus aureus bacteremia? A protocol for the adjunctive treatment domain of the S. aureus Network Adaptive Platform (SNAP) randomized controlled trial

The use of adjunctive antibiotics directed against exotoxin production in Staphylococcus aureus bacteremia (SAB) is widespread, and is recommended in many guidelines, but there is limited evidence underpinning this.

Research

Financial incentives to motivate treatment for hepatitis C with direct acting antivirals among Australian adults

Untreated hepatitis C virus (HCV) infection can result in cirrhosis and hepatocellular cancer. Direct-acting antiviral (DAA) therapies are highly effective and have few side effects compared to older interferon-based therapy. Despite the Australian government providing subsidised and unrestricted access to DAA therapy for chronic HCV infection, uptake has not been sufficient to meet the global target of eliminating HCV as a public health threat by 2030.