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News & Events

New Aboriginal Cultural Guidance Advisor appointed

The Wesfarmers Centre of Vaccines and Infectious Diseases has appointed Mrs Valerie Swift to a newly created Aboriginal Cultural Guidance Advisor position.

News & Events

Thrive by Five TED Talk - Have you met Molly?

ORIGINS Director, Prof Desiree Silva is playing an integral role in promoting a Thrive by Five TED Talk asking parents to engage more meaningfully and often with children in order to promote their brain development and set them up for life.

Antenatal Sample Collection

Instructions on the various antenatal samples collected by the Origins project and how to collect them.

News & Events

Sports Coaching Resources

Developing educational exercise resources to improve awareness and knowledge of Type 1 Diabetes (T1D) within community sport settings. Community

News & Events

Toddlers and diabetes

Caring for a child with type 1 diabetes is challenging, and perhaps even more so when the child is a toddler. Mindful of this and considering the unique needs of families caring for very young children with type 1 diabetes, PCH's Diabetes Clinic is currently

Research

Vitamin D deficiency at melanoma diagnosis is associated with higher Breslow thickness

Background: Epidemiological evidence shows that people with thicker, or higher stage, melanomas have lower vitamin D status compared to those with thinner...

Research

Population-Modifiable Risk Factors Associated With Childhood Stunting in Sub-Saharan Africa

Identifying modifiable risk factors associated with childhood stunting in sub-Saharan Africa (SSA) is imperative for the development of evidence-based interventions and to achieve the Sustainable Development Goals. The objective was to evaluate key modifiable risk factors associated with childhood stunting in SSA. 

Research

Novel intranasal phage-CaEDTA-ceftazidime/avibactam triple combination therapy demonstrates remarkable efficacy in treating Pseudomonas aeruginosa lung infection

Given the rise of multidrug-resistant (MDR) Pseudomonas aeruginosa infections, alternative treatments are needed. Anti-pseudomonal phage therapy shows promise, but its clinical application is limited due to the development of resistance and a lack of biofilm penetration. 

Research

Determining the Optimal Methodology for Identifying Incident Stroke Deaths Using Administrative Datasets Within Australia

Quantifying stroke incidence and mortality is crucial for disease surveillance and health system planning. Administrative data offer a cost-effective alternative to "gold standard" population-based studies. However, the optimal methodology for establishing stroke deaths from administrative data remains unclear.  

Research

Macrophage PD-1 associates with neutrophilia and reduced bacterial killing in early cystic fibrosis airway disease

Macrophages are the major resident immune cells in human airways coordinating responses to infection and injury. In cystic fibrosis, neutrophils are recruited to the airways shortly after birth, and actively exocytose damaging enzymes prior to chronic infection, suggesting a potential defect in macrophage immunomodulatory function.