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Virus detection and its association with symptoms during influenza-like illness in a sample of healthy adultsOur findings indicate that a greater number of symptoms are displayed by individuals presenting with influenza confirmed ILI compared with other agents that...
Research
A randomized, controlled, phase 1/2 trial of a neisseria meningitidis serogroup B bivalent rLP2086 vaccine in healthy children and adolescentsFactor H binding protein (also known as LP2086) is a conserved outer membrane neisserial lipoprotein that has emerged as a strong candidate protein antigen...
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A geometric morphometric assessment of hand shape and comparison to the 2D: 4D digit ratio as a marker of sexual dimorphismIn this study of hand shape analysis, we introduce the reader already familiar with the field of twin research to the potential utility of geometric...
Research
An eleven-year evaluation of the effect of community treatment orders on changes in mental health service useMany studies of compulsory community treatment have assessed their effect early on after the implementation of legislation.
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Gender difference in the relationship between passive smoking exposure and HDL-cholesterol levels in late adolescenceThis study has shown a gender difference in the relationship between passive smoking exposure since birth and HDL-C in late adolescence.
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Mental health in female veterinarians: Effects of working hours and having childrenMore than one-third (37%) of the sample was suffering 'minor psychological distress', suggesting the stressful nature of veterinary practice.
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Immunization of newborns with bacterial conjugate vaccinesBacterial conjugate vaccines are based on the principle of coupling immunogenic bacterial capsular polysaccharides to a carrier protein to facilitate the...
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Proteomics confirms immune stabilizing effects of narrowband UVB treatment in patients with clinically isolated syndrome and multiple sclerosisMultiple sclerosis (MS) demonstrates a latitude gradient in prevalence and severity, implicating ultraviolet B (UVB) exposure and photoimmune mechanisms in disease risk and progression. While narrowband (NB)-UVB phototherapy has long stabilized inflammation in dermatology, its systemic immunomodulatory effects in MS remain incompletely defined.
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Achieving cultural safety in genetic counseling for Aboriginal and Torres Strait Islander people in AustraliaGlobally, Indigenous people, including Aboriginal and Torres Strait Islander people in Australia, experience significantly poorer health outcomes than their non-Indigenous counterparts. In part, this can be attributed to the ongoing impacts of colonization, marginalization, and systemic discrimination. In the genomic healthcare era, Indigenous people remain underrepresented in public genetic health services, raising concerns about cultural competency and inclusivity within the genetic counseling profession.
Research
Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanomaA range of microbiota species correlate with improved cancer outcomes in patients and confer protection in pre-clinical mouse models. Here, we examined how microbiota regulate CD8+ T cell immunity against melanoma. Spontaneous control of cutaneous melanoma in mice correlated with metabolic pathways required for microbial synthesis of short-chain fatty acids (SCFAs) shared between several microbiota species.