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Interactions between innate and adaptive immunity in asthma pathogenesis: new perspectives from studies on acute exacerbationsAtopic asthma, which is at its highest prevalence during childhood/young adulthood, represents the main focus of this review.
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Self-citation in American Physiological Society JournalsThis study investigates the incidence of self-citation (authors citing their own work) for scholarly articles in ten journals published by the American...
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Increased exhaled nitric oxide in wind and brass musiciansPlaying a wind or brass (W/B) instrument is considered a strenuous activity for the respiratory system.
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Antimicrobial susceptibility of Moraxella catarrhalis isolated from children in Kalgoorlie-BoulderTo investigate antimicrobial susceptibility of Moraxella catarrhalis isolated from a cohort of children being followed in a study of the natural history of OM
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Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemiaPre-clinical models that effectively recapitulate human disease are critical for expanding our knowledge of cancer biology and drug resistance mechanisms.
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Interpretation of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine is adversely affected by methodological inaccuracies when using a commercial ELISAThe DNA lesion 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), a urinary marker of oxidative stress, is produced from reactions of reactive oxygen
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The transient value of classifying preschool wheeze into episodic viral wheeze and multiple trigger wheezeA recently proposed method for classifying preschool wheeze is to describe it as either episodic (viral) wheeze or multiple trigger wheeze.
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Apolipoprotein E genotype is associated with serum C-reactive protein but not abdominal aortic aneurysmWe assessed the association between ApoE genotype with AAA presence and growth, and serum C-reactive protein (CRP).
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Extreme weather events, home damage, and the eroding locus of controlThe catastrophic consequences of natural disasters on social and economic systems are extensively documented, yet their influence on individuals' sense of control over their life outcomes remains unexplored. This study pioneers an investigation into the causal effects of natural disaster-related home damage on the locus of control.
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Perspectives on the origin and therapeutic opportunities in Down syndrome-associated leukemiaIt is now well accepted that germline or de novo genetic alterations predispose to cancer development, especially during childhood. Among them, constitutive trisomy 21, also known as Down syndrome (DS), has been shown to predispose to acute leukemia affecting both the myeloid (ML-DS) and lymphoid (DS-ALL) lineages. ML-DS is associated with a good prognosis compared to children without DS, due in part to a higher sensitivity to conventional chemotherapy.