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Genome mining and characterisation of a novel transaminase with remote stereoselectivityHere we report a novel ω-transaminase discovered in a marine sponge Pseudovibrio sp. isolate
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Pcv7-and pcv10-vaccinated otitis-prone children in new zealand have similar pneumococcal and haemophilus influenzae densities in their nasopharynx and middle earPCV10 did not reduce NTHi density in the nasopharynx or middle ear, and was associated with increased pneumococcal nasopharyngeal density
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Baseline incidence of adverse birth outcomes and infant influenza and pertussis hospitalisations prior to the introduction of influenza and pertussis vaccinationThese baseline data are essential to assess the safety and effectiveness of influenza and pertussis vaccinations in pregnant women from the NT
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Integration of genetics and miRNA-target gene network identified disease biology implicated in tissue specificityOur result highlighted that miRNA-target gene network contributes to human disease genetics in a cell type-specific manner
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Severe and Complicated Varicella and Associated Genotypes 10 Years After Introduction of a One-Dose Varicella Vaccine ProgramSevere hospitalized varicella still occurs with a 1-dose varicella program, although predominantly in unvaccinated children
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Developing evidence-based recommendations for optimal interpregnancy intervals in high-income countries: Protocol for an international cohort studyWe aim to assess the impact of interpregnancy intervals on maternal and child health outcomes in high-income countries
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Tissue-resident memory CD8+ T cells promote melanoma–immune equilibrium in skinOur results show that TRM cells have a fundamental role in the surveillance of subclinical melanomas in the skin by maintaining cancer-immune equilibrium
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Vaccine acceptance: Science, policy, and practice in a ‘post-fact’ worldWe must continue our efforts to promote vaccine acceptance and thus increase vaccination uptake, by fostering more effective vaccination communication
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Age at menarche and childhood body mass index as predictors of cardio-metabolic risk in young adulthood: A prospective cohort studyEarlier age at menarche may be indicative of a higher risk profile for cardiovascular disease in young adulthood
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Are children more vulnerable to mesothelioma than adults?We found no greater susceptibility to mesothelioma among those first exposed to asbestos as children than those first exposed as adults