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Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

We find that DNA methylation in neonatal blood is associated with birthweight, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation

The time lag prior to the rise in glucose requirements to maintain stable glycaemia during moderate exercise in a fasted insulinaemic state is of short duration

There is a 20-min low exogenous glucose demand period during which the glucose requirements to maintain stable glycaemia do not increase during moderate exercise

Effect of 6 months of hybrid closed-loop insulin delivery in adults with type 1 diabetes: A randomised controlled trial protocol

Determine the effectiveness of 6 months' closed-loop compared with manually determined insulin dosing on time-in-target glucose range in adults with type 1 diabetes

ISPAD Clinical Practice Consensus Guidelines 2018: Assessment and management of hypoglycemia in children and adolescents with diabetes

Hypoglycemia is the commonest acute complication of type 1 diabetes

ISPAD Clinical Practice Consensus Guidelines 2018: Exercise in children and adolescents with diabetes

Promotion of regular physical activity is an integral part of diabetes care delivery and health care providers should promote this message at every available opportunity

What life is like living with type 1 diabetes

Every decision a child with type 1 diabetes makes can impact on their blood glucose levels.

Characteristics of Automated Insulin Suspension and Glucose Responses with the Predictive Low-Glucose Management System

Longer suspends and fewer glycemic excursions occur at night compared with day

Real-world outcomes of insulin pump compared to injection therapy in a population-based sample of children with type 1 diabetes

Patients using insulin pump therapy had a better long-term glycemic control relative to the matched injection therapy cohort

Use of Continuous Glucose Monitoring Trends to Facilitate Exercise in Children with Type 1 Diabetes

This study investigated the use of a carbohydrate intake algorithm based on continuous glucose monitoring trends during physical activity

National Hybrid Closed-Loop Outpatient Trial

The national Hybrid Closed-Loop Outpatient Trial will test the use of an automated insulin delivery system to see if it is better at optimising blood glucose levels than standard therapy.