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Research
Ovulation induction and subfertile untreated conception groups offer improved options for interpreting risks associated with ARTTo identify and characterise appropriate comparison groups for population studies of health outcomes in ART-conceived births: ovulation induction (OI), subfertile untreated and fertile natural conceptions. Our secondary objective was to examine whether known risks of pregnancy complications and adverse birth outcomes in ART births are elevated in comparison with subfertile (untreated and OI) conception groups.
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PKC activation promotes maturation of cord blood T cells towards a Th1 IFN-γ propensityA significant number of babies present transiently with low protein kinase C zeta (PKCζ) levels in cord blood T cells, associated with reduced ability to transition from a neonatal Th2 to a mature Th1 cytokine bias, leading to a higher risk of developing allergic sensitisation, compared to neonates whose T cells have 'normal' PKCζ levels. However, the importance of PKCζ signalling in regulating their differentiation from a Th2 to a Th1 cytokine phenotype propensity remains undefined.
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Parents’ experience and psychoeducation needs when supporting a young person who self-harmsThe study highlights the need for support for parents and carers of young people who engage in self-harm
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IgG3 + B cells are associated with the development of multiple sclerosisWe have identified previously uncharacterised subsets of IgG3 + B cells and shown them to correlate with autoimmune attacks on the central nervous system
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COPD-related modification to the airway epithelium permits intracellular residence of nontypeable haemophilus influenzaeOur findings indicate that COPD, cigarette smoke and macrolide antibiotics potentiate the susceptibility to persistent intracellular NTHi
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Immune function during early adolescence positively predicts adult facial sexual dimorphism in both men and womenOur results support a fundamental assumption that facial sexual dimorphism is an indicator of immune function during the development of facial sexual dimorphism
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Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflowsSystematic comparison of recovered cell types and their transcriptional profiles across the workflows has highlighted protocol-specific biase
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Elastase Exocytosis by Airway Neutrophils Associates with Early Lung Damage in Cystic Fibrosis ChildrenProtease elastase exocytosis by airway neutrophils occurs in all cystic fibrosis children, and its cellular measure correlates with early lung damage
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A Comparison of the Motor Skills of Young People in a Youth Detention Centre with Diagnosed Fetal Alcohol Spectrum Disorder and Prenatal Alcohol ExposureVisual motor integration and handwriting skills were often impaired in this population of young people in a youth detention centre
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What is known about consumer nutrition environments in Australia? A scoping review of the literatureThis study aimed to summarize the attributes that have been examined in existing peer-reviewed studies of Australian consumer nutrition environments