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Sialic acid-to-urea ratio as a measure of airway surface hydrationWe explored a robust method to estimate mucus hydration using sialic acid as a marker for mucin content.
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Repeat pneumococcal polysaccharide vaccine in Indigenous Australian adults is associated with decreased immune responsivenessThese findings highlight the critical need to evaluate the efficacy of future pneumococcal vaccine programs in the Australian Indigenous populations that recommend repeated doses of 23vPPV.
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Population-based estimates of the effectiveness of pneumococcal vaccination in AustraliaAustralia’s Childhood Immunisation Register (ACIR) is one of only a handful of national immunisation registers world-wide.
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Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990-2015: findings from the Global Burden of Disease 2015 studyThe age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average.
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Randomized controlled trial of early regular egg intake to prevent egg allergyWe aimed to determine whether regular consumption of egg protein from 4-6 month old reduced the risk of IgE-mediated egg allergy in infants without eczema.
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Repeated vaccination does not appear to impact upon influenza vaccine effectiveness against hospitalization with confirmed influenzaThese findings reinforce current recommendations for annual influenza vaccination, particularly those at greatest risk of influenza disease.
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Latent Class Analysis of Neurodevelopmental Deficit After Exposure to Anesthesia in Early ChildhoodSome studies suggest an association between early exposure to anesthesia, surgery and long term developmental deficit, clinical phenotype of children is unknown
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What is the evidence for managing tone in young children with, or at risk of developing, cerebral palsy: a systematic reviewTo conduct a systematic review of the evidence for the management of tone in infants 0-24 months of age, with or at risk of developing cerebral palsy.
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Associations of Early- and Later-Childhood Poverty with Child Cognitive Function in Indonesia: Effect Decomposition in the Presence of Exposure-Induced Mediator-Outcome ConfoundingOur analysis shows that early and late intervention to support household income have equal importance with regards to significance of impact.
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Structure-diverse Phylomer libraries as a rich source of bioactive hits from phenotypic and target directed screens against intracellular proteinsPhylomer libraries are being increasingly used in applications such as phenotypic screening where the numbers of peptides which can be feasibly screened is limited