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Airway smooth muscle thickness and contraction are enhanced by intra-amniotic lipopolysaccharide in an ovine model of premature birthAbnormalities of the airway smooth muscle (ASM) layer in asthma may develop before birth. We hypothesize that antenatal inflammation causes physiological abnormalities of the ASM that predisposes asthma. This study determined the short-term effects of antenatal inflammation on the developing ASM.
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The impact a Mediterranean Diet in the third trimester of pregnancy has on neonatal body fat percentageMaternal diet during pregnancy has long been recognised as an important determinant of neonatal outcomes and child development. Infant body composition is a potentially modifiable risk factor for predicting future health and metabolic disease.
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Lao PDR early childhood education project : snapshot four - services and facilitiesThis snapshot highlights that early education services are related to better levels of early child development, but coverage and access is not sufficient
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Physiological responses to exercise in survivors of preterm birth: a meta-analysisSurvivors of preterm birth (<37 weeks' gestation) have low peak oxygen uptake, a global measure of aerobic fitness and an established predictor of increased morbidity and mortality. However, little is known about other cardiopulmonary outcome measures in this population. We addressed the hypothesis that preterm birth is associated with abnormal respiratory, cardiovascular and metabolic responses to exercise, as assessed by cardiopulmonary exercise testing, via a systematic review and meta-analysis.
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Immunogenicity, Reactogenicity, and Safety of a Pentavalent Meningococcal ABCWY Vaccine in Adolescents and Young Adults who had Previously Received a Meningococcal ACWY VaccineA MenABCWY vaccine containing 4CMenB and MenACWY-CRM vaccine components has been developed to protect against the 5 meningococcal serogroups that cause most invasive disease cases.
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Whole-of-Life Inclusion in Bayesian Adaptive Platform Clinical TrialsThere is a recognized unmet need for clinical trials to provide evidence-informed care for infants, children and adolescents. This Special Communication outlines the capacity of 3 distinct trial design strategies, sequential, parallel, and a unified adult-pediatric bayesian adaptive design, to incorporate children into clinical trials and transform this current state of evidence inequity. A unified adult-pediatric whole-of-life clinical trial is demonstrated through the Staphylococcus aureus Network Adaptive Platform (SNAP) trial.
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Factors for Children's Receptive Vocabulary Development from Four to Eight Years in the Longitudinal Study of Australian ChildrenVariation in receptive vocabulary ability is associated with variation in children's school achievement, and low receptive vocabulary ability is a risk...
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Brief Report: Further Evidence for a Link Between Inner Speech Limitations and Executive Function in High-Functioning Children with AutismThis study investigated the involvement of inner speech limitations in the executive dysfunction associated with autism spectrum disorders (ASDs).
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Child care quality and children's cognitive and socio-emotional development: an Australian longitudinal studyThere is growing evidence that high-quality non-parental child care can contribute to children's learning, development and successful transition to school.
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Investigation of the Cross-National Equivalence of a Measurement of Early Child DevelopmentThe present study examined the psychometric properties of the domains of the 48-item EDI and the invariance of the measurement models of the domains of the...