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ORIGINS is fortunate to have a small passionate and dedicated group of longstanding volunteers.
The ORIGINS Biobank is collecting biological samples from participant families at 10 timepoints between the time of pregnancy and the child turning five years of age.
The Antenatal Colostrum Expression (ACE) Study aims to determine whether hand expressing of colostrum in the last few weeks of pregnancy can help new mothers to breastfeed.
Research
Using acute tryptophan depletion to investigate predictors of treatment response in adolescents with major depressive disorderThe major hypothesis of this study is that acute tryptophan depletion will be negatively associated with mood and cognitive functioning
Research
WHO/IUIS Allergen Nomenclature: Providing a common languageAim was to standardize the names given to the antigens (allergens) that caused IgE-mediated allergies in humans
Research
Motor abnormalities in Rett SyndromeFor most individuals, there is initial developmental progress followed by regression at around 6–30 months. The classic signs of RTT then become apparent.
Research
Clinical, research, and public health implications of poor measurement of Vitamin D statusNew initiatives to develop a standard reference method and the assignment of "true" values to samples provide a solution to these problems.
Research
Altered regulatory T-cell fractions and Helios expression in clinically isolated syndrome: clues to the development of multiple sclerosisThese results indicate that T regulatory (Treg) and follicular T regulatory (Tfr) impairment is an early feature in MS.
Research
Severe winter asthma exacerbations can be prevented by omalizumab, but there is no carryover effect.Recurrent severe asthma exacerbations are associated with decreased lung growth or accelerated loss of long function and add substantially to cost and morbidity
Research
Identification and characterization of a dendritic cell precursor in parenchymal lung tissueThis is the first study to describe a pulmonary precursor cell for dendritic cells in lung tissue