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Research

The gut microbiome and cardiovascular disease: current knowledge and clinical potential

This review will focus on the role of the gut microbiome and associated functional components in the development and progression of atherosclerosis

Research

Environmental and social determinants of acute rheumatic fever: a longitudinal cohort study

Prevention strategies in ARF endemic settings may be enhanced by targeting new members entering a community and children in environments of close contact

Research

Dysregulated IL-1β-GM-CSF Axis in Acute Rheumatic Fever That Is Limited by Hydroxychloroquine

We propose that hydroxychloroquine could be repurposed to reduce the risk of rheumatic heart disease after acute rheumatic fever

Research

Maternal pre-pregnancy weight and autistic-like traits among offspring in the general population

This study provides further evidence that maternal pre-pregnancy obesity is associated with autism-like behaviors in offspring

Research

Characterizing the interplay between autism spectrum disorder and comorbid medical conditions: An integrative review

We review medical conditions that have been repeatedly highlighted as sharing the strongest associations with ASD-epilepsy, sleep, as well as gastrointestinal and immune functioning

Research

The ORIGINS Project

ORIGINS is a new birth cohort study, collecting detailed information about the early environment's influence on a broad range of non-communicable diseases

Research

Risk of Developmental Disorders in Children of Immigrant Mothers: A Population-Based Data Linkage Evaluation

Increased risk of autism spectrum disorder with intellectual disability and cerebral palsy with intellectual disability for mothers of some foreign-born groups

Research

Screening for HIV-Associated Neurocognitive Impairment: Relevance of Psychological Factors and Era of Commencement of Antiretroviral Therapy

Findings of the Montreal Cognitive Assessment were not confounded by existing mood disorders, unlike the 3-item questionnaire

Research

Silver Russel syndrome in an aboriginal patient from Australia

We report a 4-year-old Australian Aboriginal girl who was born at 32 weeks gestation with features strongly suggestive of Silver-Russell syndrome

Research

Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA study

Immunomodulatory proteins in human milk (HM) can shape infant immune development. However, strategies to modulate their levels are currently unknown. This study investigated whether maternal prebiotic supplementation alters the levels of immunomodulatory proteins in HM.