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A systems biology approach to better understand human tick-borne diseasesTick-borne diseases are a growing global health concern. Despite extensive studies, ill-defined tick-associated pathologies remain with unknown aetiologies. Human immunological responses after tick bite, and inter-individual variations of immune-response phenotypes, are not well characterised.
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Effects of zinc and vitamin A supplementation on prognostic markers and treatment outcomes of adults with pulmonary tuberculosis: a systematic review and meta-analysisUndernutrition is a major risk factor for tuberculosis (TB), which is estimated to be responsible for 1.9 million TB cases per year globally. The effectiveness of micronutrient supplementation on TB treatment outcomes and its prognostic markers (sputum conversion, serum zinc, retinol and haemoglobin levels) has been poorly understood.
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Does a 10-valent pneumococcal-Haemophilus influenzae protein D conjugate vaccine prevent respiratory exacerbations in childrenOur study will be the first to assess vaccine efficacy targeting H. influenzae in children with recurrent PBB, CSLD and bronchiectasis.
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Streptococcus pneumoniae and Haemophilus influenzae in paediatric meningitis patients at Goroka General HospitalThis research presents serotype, antimicrobial susceptibility and outcome data from paediatric meningitis patients prior to introduction of Haemophilus...
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Home oxygen therapy for infants and young children with acute bronchiolitis and other lower respiratory tract infections: The HiTHOx programRecent studies have demonstrated that some children with acute bronchiolitis can be successfully managed using home oxygen therapy.
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Factors associated with respiratory morbidity in children, adolescents and young adults with cerebral palsyThe primary aim of this study is to identify the predictors and prevalence of severe respiratory disease in children, adolescents and young adults with CP.
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Exploring the dynamics of respiratory syncytial virus (RSV) transmission in childrenWe develop a compartmental model for RSV infection, driven by a seasonal forcing function, and conduct parameter space and bifurcation analyses to document...
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Host genetic factors in American cutaneous leishmaniasis: A critical appraisal of studies conducted in an endemic area of BrazilThis paper reviews American cutaneous leishmaniasis (ACL) immunogenetics in the state of Bahia (BA), northeastern Brazil, highlighting the interacting roles...
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Mother's love for bacterial babies: the commitment of Audrey Michael, Mition Yoannes and Tilda Orami to medical researchFace-to-face interviews were conducted with all three women for the purpose of profiling women who are leaders in health and medicine in Papua New Guinea.
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STopping Acute Rheumatic Fever Infections to Strengthen Health (STARFISH)STopping Acute Rheumatic Fever Infections to Strengthen Health (STARFISH) brings together a diverse and multidisciplinary research team to investigate the most effective environmental health initiatives (EHIs) aimed at reducing Strep A infections and prevent Acute Rheumatic Fever (ARF).